3 ms·

Another counterpoint - AlphaFold. It really discovers structure we could not previously discover.

• dekhn 4y ago
  Not really- all of alphafold depends on having enough sequence alignment information to existing proteins with known structures. It really does not perform all that well on out-of-dataset prediction.
  • fsloth 4y ago
    Still having good combinatorical guestimates extrapolated from existing knowledge is not a useless trick in itself.
    • visarga 4y ago
      If you can simulate you can check and throw out the garbage, or get more training data for the next iteration.