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Embryo selection based on genome sequencing is already being done: https://astralcodexten.substack.com/p/welcome-polygenically-screened-babies?s=r https://astr

• dekhn 5y ago
  Your example is "genetic" testing- it only samples a limited number of locations in the genome. This method is more like whole genome sequencing.
  • abcc8 5y ago
    There really aren't that many reasons to sequence the entire genome in this context. Specific disease causing mutations in the parents can be specifically targeted in the embryo/fetus. Similarly, PRS scores don't require full genome sequencing to generate (but also aren't ready for prime time routine usage). Also, aneuploidy detection doesn't require genome sequencing. This is just a few examples.
    • dekhn 5y ago
      I was just pedantically correcting the person I was replying to.
• Metacelsus 5y ago
  This method is similar, but uses the parents' genomic data to improve predictions of the embryo's genome (since sequencing only a few cells gives low-quality data).