5 ms·

You also seem confused. Yes, some people are interested in Ivermectin as a protease inhibitor. But the reason the de-wormer came to prominence in the first plac

You also seem confused. Yes, some people are interested in Ivermectin as a protease inhibitor. But the reason the de-wormer came to prominence in the first place was because some lower quality studies found it has a positive effect on COVID-19 outcomes. The most famous study in this collection came out of Brazil. But the reason that study found a positive impact from Ivermectin is that parasites are a harmful COVID co-morbidity, Ivermectin effectively treats parasites, and a lot of people in Brazil are afflicted with parasites.

conradfr 5y ago
Not entirely true as there was a retirement home in France during the first outbreak where residents were treated with Ivermectin due to scabies where they had no Covid deaths and less bad cases than the other surrounding homes. But I guess it was not replicated.
- evan_ 5y ago
  Scabies is caused by a parasitic mite. This example likely supports the “parasite” theory.
  - conradfr 5y ago
    But not the "third world bad health" theory so much.
- zackees 5y ago
CapmCrackaWaka 5y ago
You and the parent comment are in complete agreement. They even said, in the first sentences: > Yes, ivermectin is an anti-parasitic, and yes that's probably why there's anecdotal evidence of it working. The reason people are testing it is because it has potential anti-viral properties as well. And then you said: > Yes, some people are interested in Ivermectin as a protease inhibitor. But the reason the de-wormer came to prominence in the first place was because some lower quality studies found it has a positive effect on COVID-19 outcomes.
- jjoonathan 5y ago
  Hey, prohobo was first to agree completely with the parent post: > Yes, ivermectin is an anti-parasitic, and yes that's probably why there's anecdotal evidence of it working. and then shit on it for not discussing their pet theory: > it's funny how badly you misunderstand the situation
  - prohobo 5y ago
    That pet theory is what got it classified as a drug of interest in the first place. That's why most of us even know what ivermectin is.
throwawaycities 5y ago
> But the reason that study found a positive impact from Ivermectin is that parasites are a harmful COVID co-morbidity, Ivermectin effectively treats parasites, and a lot of people in Brazil are afflicted with parasites. Can you link the follow up study confirming this?
marcosdumay 5y ago
> The most famous study in this collection came out of Brazil. The famous study done in Brazil was a fraudulent one, without authorization from the public health agency, where the patients that took Ivermectin had a 2 to 3 times higher mortality rate (very likely due to unrelated issues), but the numbers were cooked to make the drug look useful. That's the one with thousands of people that registered an effect. There is also another one, with dozens of people that got an week effect. This one is most likely spurious.

conradfr 5y ago

Not entirely true as there was a retirement home in France during the first outbreak where residents were treated with Ivermectin due to scabies where they had no Covid deaths and less bad cases than the other surrounding homes. But I guess it was not replicated.

evan_ 5y ago
Scabies is caused by a parasitic mite. This example likely supports the “parasite” theory.
- conradfr 5y ago
  But not the "third world bad health" theory so much.
zackees 5y ago

CapmCrackaWaka 5y ago

You and the parent comment are in complete agreement. They even said, in the first sentences: > Yes, ivermectin is an anti-parasitic, and yes that's probably why there's anecdotal evidence of it working. The reason people are testing it is because it has potential anti-viral properties as well. And then you said: > Yes, some people are interested in Ivermectin as a protease inhibitor. But the reason the de-wormer came to prominence in the first place was because some lower quality studies found it has a positive effect on COVID-19 outcomes.

jjoonathan 5y ago
Hey, prohobo was first to agree completely with the parent post: > Yes, ivermectin is an anti-parasitic, and yes that's probably why there's anecdotal evidence of it working. and then shit on it for not discussing their pet theory: > it's funny how badly you misunderstand the situation
- prohobo 5y ago
  That pet theory is what got it classified as a drug of interest in the first place. That's why most of us even know what ivermectin is.

throwawaycities 5y ago

> But the reason that study found a positive impact from Ivermectin is that parasites are a harmful COVID co-morbidity, Ivermectin effectively treats parasites, and a lot of people in Brazil are afflicted with parasites. Can you link the follow up study confirming this?

marcosdumay 5y ago

> The most famous study in this collection came out of Brazil. The famous study done in Brazil was a fraudulent one, without authorization from the public health agency, where the patients that took Ivermectin had a 2 to 3 times higher mortality rate (very likely due to unrelated issues), but the numbers were cooked to make the drug look useful. That's the one with thousands of people that registered an effect. There is also another one, with dozens of people that got an week effect. This one is most likely spurious.