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Some key points from the article are listed below. But full explanations and cautions are in the article. This data is from the UK Health Security Agency (UKHSA
by vanilla-almond 5y ago
Some key points from the article are listed below. But full explanations and cautions are in the article. This data is from the UK Health Security Agency (UKHSA).
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Protection against death (mortality)
Vaccine effectiveness against death (mortality) from Omicron in those aged over 50 (it is too early to produce accurate data for those aged under 50):
- After two doses: 59% after twenty-five weeks
- After a booster dose: 95% after two weeks
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Protection against severe disease requiring hospitalisation from Omicron
- After two doses of any vaccine: 25-35% protection after twenty-five weeks
- After a Pfizer booster: around 90%, dropping to around 75% after ten to fourteen weeks
- After a Moderna booster: 90-95% up to nine weeks after vaccination
Hospitalisations prevented: Latest analysis estimates the boosters alone prevented 105,600 hospitalisations in those aged 25 and over in England between December 13 2021 and February 6 2022.
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Protection against symptomatic disease (mild infection)
- After two doses of AstraZeneca: around 50% protection, waning to almost 0% from twenty weeks
- After two doses of Pfizer or Moderna: 65-75% protection, waning to around 10% by twenty-five weeks after the second dose
- After a booster dose: 65-75% protection after two to four weeks, waning to 30-40% after fifteen weeks
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Protection against infection (including asymptomatic infection)
Vaccine effectiveness against infection from Delta (including asymptomatic infection):
- After two doses of AstraZeneca: Estimated at around 50% after two months
- After two doses of Pfizer: Estimated at around 81% after two months, waning to around 46% after six months
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Prevention of transmission
Effectiveness of the vaccines against transmission of the Delta variant:
- After two doses of AstraZeneca: Estimated at 42%
- After two doses of Pfizer: Estimated at 31%
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Additional vaccine protection for those with prior infection (infection-derived immunity)
Early evidence shows that getting vaccinated after infection provides significantly higher levels of protection against reinfection. Protection against reinfection from Omicron:
- No vaccination and prior infection: Estimated at 44%
- Prior infection and three vaccine doses: Estimated at 71%
- Tomminn 5y agoNote the bait switch to Delta when transmission and infection are mentioned.
- deleted 5y ago[deleted]
- fknorangesite 5y agoThe way you phrased this it sounds like they're being intentionally misleading, but it's directly addressed in the article: there just aren't good, complete studies on this for Omicron yet. For example: > A rapid analysis from the SIREN study showed lower protection from both vaccination and previous infection to Omicron compared to Delta, but indicated higher protection among those who had received booster vaccination. and > Comprehensive analysis is ongoing into exactly how much additional protection the vaccines provide against Omicron infections, but a rapid unadjusted analysis from the SIREN study indicated an increasing benefit of each vaccine dose in those with prior infection. Note "rapid analysis" for the Omicron.
- Tomminn 5y agoI think that if those studies showed large reductions in transmission and infection of omicron with vaccination then they wouldn't provide the disclaimer that these studies are not good and complete. Why are the studies that show substantial omicron hospital reductions and death reductions from vaccines good and complete? By what metric do these articles differ from those which show vaccines barely budge infection and transmission rates? Often both claims (substantial hosp/death reduction, minimal infec/trans reduction) are found in the same damn paper. Also everyone knows many people scan articles, and it feels like the format of this article is intentionally constructed to deceive those people. I would estimate 60% of readers come away with the impression those transmission and infection reductions are for omicron. The only reason I didn't make that mistake was because I knew those numbers for omicron were super far off from what is currently understood, and so I read the article more closely that I ordinarily would an article in this format.
- raxxorrax 5y agoThis hits completely new levels of conjecture. This is fortune teller level science.
- nojokes 5y agoAs you do not elaborate any further, your comment has very little value.