4 ms·

Medical Keto seems like something that is super legit and very interesting. "Popular" keto interests me a lot less. What is the reason it chemically or physica

Medical Keto seems like something that is super legit and very interesting. "Popular" keto interests me a lot less. What is the reason it chemically or physicals works for seizure disorders? Not to directly compare them but I feel the same way about a lot of rhetoric around CBD - there are a lot of approved and legitimate medical uses but the amount of extra stuff that people claim it does seems like total BS.

throwawayanon47 5y ago
re: Keto for seizures: They dont actually know why it works. But on keto your cells are working on a completely different energy source so there's whole metabolic chains that are completely different. I think the leading theory is its one of the by-products of those metabolic chains, rather than the ketones themselves. Some say gut bacteria have a role in it too. re: CBD: Interestingly, Dravet Syndrome is also shown to react fairly well to CBD. If you've heard of the 'Charlottes web' strain of cannabis and all that stuff, that was named after Charlotte Figi who had Dravet Syndrome. CBD is used quite widely to treat Dravet - there's been a lot of research and there's now an 'official' pharmaceutical CBD called Epidolex https://www.webmd.com/drugs/2/drug-176175/epidiolex-oral/details https://www.webmd.com/drugs/2/drug-176175/epidiolex-oral/det... - approved by the FDA, NHS etc. You can get it on prescription over here. Theres a certain 'pot cures everything' lobby that have overblown it a bit. It does seem to work but there are side effects and there are other drugs that work just as well or better (with the caveat that with epilepsy, not every patient responds the same to every drug). e.g. Fenfleuramine is another new (or technically, repurposed) drug for Dravet that seems to work better than CBD for most people. Although I have met some Dravet parents who swear by CBD and say they've done great with it. Others say that CBD on its own isn't enough, you need proper cannabis.
loudtieblahblah 5y ago
I did strict, high ratio, keto for 6 months. I did it pretty "clean" too. I almost never strayed above 50g carbs a day and usually stayed under 20g. My fat ratio made up 70% of my diet. No processed foods. Lots of veggies. My years of indigestion went away (and never came back - it's been 3.5 years since this experiment) Lost 60lbs from 220 to 160. Slept like a log. Like a solid 7-9hrs a night once I was a month in. All my markers - lipids, metabolic, blood Glucose, etc..went from shit to within norms with LDL slightly elevated. I had more energy during the day, and way more focus (I'm adhd). I had to quit bc even when upping my calories to 2,500-3k a day. I was still losing weight. Also I developed Orthorexia during this process. I became obsessed with making keto versions of bread, taco shells, home made cereal, and started to spend endless amounts of time in the kitchen. When eggs, meat and big ass salads would have done just fine. Even when quitting keto.. Taking nutrition to absurd degrees was common for years. It became a total OCD.

throwawayanon47 5y ago

re: Keto for seizures: They dont actually know why it works. But on keto your cells are working on a completely different energy source so there's whole metabolic chains that are completely different. I think the leading theory is its one of the by-products of those metabolic chains, rather than the ketones themselves. Some say gut bacteria have a role in it too. re: CBD: Interestingly, Dravet Syndrome is also shown to react fairly well to CBD. If you've heard of the 'Charlottes web' strain of cannabis and all that stuff, that was named after Charlotte Figi who had Dravet Syndrome. CBD is used quite widely to treat Dravet - there's been a lot of research and there's now an 'official' pharmaceutical CBD called Epidolex https://www.webmd.com/drugs/2/drug-176175/epidiolex-oral/details https://www.webmd.com/drugs/2/drug-176175/epidiolex-oral/det... - approved by the FDA, NHS etc. You can get it on prescription over here. Theres a certain 'pot cures everything' lobby that have overblown it a bit. It does seem to work but there are side effects and there are other drugs that work just as well or better (with the caveat that with epilepsy, not every patient responds the same to every drug). e.g. Fenfleuramine is another new (or technically, repurposed) drug for Dravet that seems to work better than CBD for most people. Although I have met some Dravet parents who swear by CBD and say they've done great with it. Others say that CBD on its own isn't enough, you need proper cannabis.

loudtieblahblah 5y ago

I did strict, high ratio, keto for 6 months. I did it pretty "clean" too. I almost never strayed above 50g carbs a day and usually stayed under 20g. My fat ratio made up 70% of my diet. No processed foods. Lots of veggies. My years of indigestion went away (and never came back - it's been 3.5 years since this experiment) Lost 60lbs from 220 to 160. Slept like a log. Like a solid 7-9hrs a night once I was a month in. All my markers - lipids, metabolic, blood Glucose, etc..went from shit to within norms with LDL slightly elevated. I had more energy during the day, and way more focus (I'm adhd). I had to quit bc even when upping my calories to 2,500-3k a day. I was still losing weight. Also I developed Orthorexia during this process. I became obsessed with making keto versions of bread, taco shells, home made cereal, and started to spend endless amounts of time in the kitchen. When eggs, meat and big ass salads would have done just fine. Even when quitting keto.. Taking nutrition to absurd degrees was common for years. It became a total OCD.