4 ms·
Oxytocin nasal spray apparently makes an autistic guy not autistic
- kadoban 5y agoVery interesting, but it's also a twitter summary of a random reddit post, so I'm thinking this is unlikely to be true.
- kylebenzle 5y agoRead the post, not the Tweet lol.
- kadoban 5y agoThen it's still just some random reddit post.
- sergiomattei 5y agoX for Doubt, but interesting nonetheless. Not so sure about spraying psychoactive chemicals up my brain without more trip reports though… Edit: apparently a study found it ineffective https://www.spectrumnews.org/news/intranasal-oxytocin-ineffective-for-autism-in-large-trial/amp/ https://www.spectrumnews.org/news/intranasal-oxytocin-ineffe...
- aaroninsf 5y agoHung out with a guy at BM for a week who swore by it. His baseline was different than the Redditor presents as theirs, but he had comparable if scaled down versions of the same claims and experience. He had brought cases of his go-to spray and was giving them out to anyone interested for self experimentation. AFAIK modulo source control there is not much risk from these nasal sprays. Tried some myself. Would not claim to be able to differentiate any affective difference from placebo and set/setting effects. Which at BM are considerable. But at the time I thought I might have gotten a peasant if mild social-anxiety and general equanimity bump.
- JPLeRouzic 5y agoI am not a native, please what is BM?
- flyingfences 5y agoIn this context, I presume that BM means Burning Man, though it took me a while to arrive at that answer.
- netizen-936824 5y agoIn my opinion, the mu-opioid receptor is a more promising target for autism (some forms of ASD anyway) https://pubmed.ncbi.nlm.nih.gov/28369738/ https://pubmed.ncbi.nlm.nih.gov/28369738/
- more_corn 5y agoThis sounds super exciting. I can’t help but wonder though... The language sounds weird. Maybe that’s because the person writing has Asperger’s, but it almost sounds like how a NT person would think someone with Asperger’s would talk. We probably need to move into the mode of requiring extraordinary evidence before we get to excited. One thought that might explain mixed study results, aren’t there like half a dozen kinds of autism? I would imagine that if the study failed to account for the difference the results could be inconsistent. It seems like a promising area of research though.
- StrictDabbler 5y agoThe Twitter commenter who described this as "neurotypicality fan-fiction" pretty much nailed it.
- aaroninsf 5y agoExpand on this? What I mean is: do you believe this is a fictional account, written by an NT, asserting an altered personal experience which conforms to NT received value structures? or, that this Redditor's account may be honest in the sense of describing their own self experience, but, compromised in the sense that it adopts NT language and value structures?
- fknorangesite 5y agoThis tweet: https://twitter.com/katestorrs/status/1485886372674260995?s=20 https://twitter.com/katestorrs/status/1485886372674260995?s=... > Like someone fantasising about what being NT would be like (maybe based on a much milder experience).
- jonnycomputer 5y agoOxytocin and autism has been studied for some time, and the use of nasal oxytocin as treatment for autism has also been studied. Better if we looked at the literature than get excited by a random reddit post reposted on twitter. e.g. https://scholar.google.com/scholar?hl=en&as_sdt=0%2C47&q=oxytocin+autism+treatment+review&btnG= https://scholar.google.com/scholar?hl=en&as_sdt=0%2C47&q=oxy...
- SubiculumCode 5y agoThanks JohnnyComputer. This is certainly true. The literature is rather deep.
- cpcallen 5y agoOriginal Reddit post: https://www.reddit.com/r/oxytocin/comments/7n1r1n/my_oxytocin_diary/ https://www.reddit.com/r/oxytocin/comments/7n1r1n/my_oxytoci...
- LazyMans 5y agoThe effects described are pretty much precisely what MDMA feels like. Weird.
- netizen-936824 5y agoThe R isomer of MDMA has a decent affinity for releasing oxytocin.