6 ms·

Totally anecdotal but my girlfriend and I recently went to wedding and even with pre testing and everyone vaccinated, a lot of people got Covid. I was super hi

Totally anecdotal but my girlfriend and I recently went to wedding and even with pre testing and everyone vaccinated, a lot of people got Covid. I was super high that night (as most nights) and walked away unscathed. Obviously this could be due to a lot of things but that hasn’t stopped me from rubbing it in all my friends faces. It’s been of the few times in my life where my weed habit looks smart, and I’m loving every minute of it.

cbsks 5y ago
A year ago my wife got Covid. She isolated in our bedroom and I was quarantined in the rest of the house. I spent my time getting high and watching movies. I took multiple PCR tests and an antibody test and they were all negative. > It’s been of the few times in my life where my weed habit looks smart, and I’m loving every minute of it. Indeed :)
selectodude 5y ago
There were some early studies that showed that nicotine had a higher affinity for ACE2 than SARS-CoV-2 and that smokers had a lower risk of catching covid. I told everybody that while ripping my camels.
- pille 5y ago
  Worth repeating that this study was retracted. Authors failed to disclose a conflict of interest in their funding from the tobacco industry: https://erj.ersjournals.com/content/57/3/2002144 https://erj.ersjournals.com/content/57/3/2002144
  - selectodude 5y ago
    In fairness, the study was retracted not due to the data but because "The European Respiratory Society, as a leading medical organisation in the respiratory field whose mission is to promote lung health and alleviate suffering from respiratory disease, has bylaws in place that do not permit individuals with ongoing relationships with the tobacco industry to participate in its activities" and in other situations, "The journal editors acknowledge that COPE (Committee on Publication Ethics) guidelines state that failure to disclose a potential conflict of interest is not normally sufficient grounds for retraction of a published article." I understand the journal's actions but I'd hesitate to say the study is wrong or has been retracted for anything beyond politics.
    - pille 5y ago
      I’m not sure what you mean by “politics” here, so I’d rather be explicit and say what it looks like to me. The tobacco industry has a rich history of trying to manipulate public opinion in their favor, and this article and authors’ undisclosed conflict of interest fits that pattern well: a study shows cigarettes are actually good for you in some way, and might even save you from the current pandemic; and then whoops, authors were getting paid by the tobacco industry, and then whoops again, they didn’t mention it when submitting for publication. If the study was retracted even though the CoPE guidelines don’t require a retraction, it implies to me that this case was more egregious than just some protocol mixup or forgetfulness. The most generous reading is that the retraction was made out of an abundance of caution and concern for the journal’s reputation. I suppose that’s possible, but I don’t see any further evidence in favor of exonerating the article, especially knowing the industry’s history.
      - selectodude 5y ago
        >I’m not sure what you mean by “politics” here, so I’d rather be explicit and say what it looks like to me. I mean that they explicitly said they retracted the study (in the journal, the authors haven't retracted anything) because they refuse to take any research from anybody who has ever accepted money from tobacco companies regardless of the rigor of the data or research. Non-academic reasons. I understand their stance because, as you said, the tobacco companies have a long sordid history of research and it's a journal of lung health with a strong "anti-smoking" bent, but calling the study "retracted" implies that it was somehow false or disproven when it has not been.
        pille 5y ago
        > the authors haven't retracted anything Why would you trust the authors, though? They really should know better. To me, the omission is either the product of general incompetence (they forgot?), or intent to deceive. Both of those seem pretty disqualifying.
  - 8bitsrule 5y ago
    Worth noting that this may or not have any bearing on the conclusions... "The manuscript presents some new data on, and provides a section of discussion of, the effect of tobacco consumption on patient susceptibility to COVID-19, and cites other studies that claim SARS-CoV-2 infection is less prevalent in smokers or tobacco users." Perhaps reading those other studies would be prejudicial. I once spend the better part of a day online looking for actual data on the known dangers of second-hand smoke. I found the not-so-surprising answers in a hard-to-find article in Lancet. It ... contradicted the mainstream tale.
    - pille 5y ago
      Could you share a link to this Lancet article?
diryawish 5y ago
I've noticed a correlation between heavy herb smokers and not getting the virus or having mild symptoms. People that primarily do hash haven't had the same benefit, which is kind of weird. This is all anecdotal.
- netizen-936824 5y ago
  How does THC intoxication change social behaviors? Are you more or less social? Personally I doubt it was a direct pharmacological effect, but rather a secondary behavioral effect
  - dekhn 5y ago
    I'm a long-time THC consumer. The effects differ tremendously based on a wide range of variables. I've also retrained myself after many years to override my natural THC behaviors. Let me give some examples. College days, my first real year of smoking, I got really high. I mean, really really high. Close to a psychedelic experience. I went to the cafe to get an ice cream sundae and when I walked in, everybody in the entire room stared at me. Or, it felt like it. 30 people making eye contact looking at me AND THEY KNOW I'M HIGH. It was extremely uncomfortable- for my entire life growing up, I hadn't really ever made eye contact with people and having a lot of it was intense. A few years later, I get really high at a Grateful Dead show. Completely different experience- everybody was getting high and having a great time with strangers and I didn't feel judged and it was GREAT, socially speaking. Following college I began my professional career, but I am also a full time smoker, so I had to learn how to deal with the "OH GOD THEY KNOW" feelings and forced myself to be highly social at parties, etc. It can be really weird to be a person who is very introverted and wants nothing more to curl up in a ball far from people, but walk around a party introducing yourself to everybody and making intelligent conversation. Im interested in the psychopharmacology of cannabis and why so many people get the paranoia effect. I suspect it's probably a side effect of tweaking your endogenous cannabinoid system, in combination with the social pressures associated with cannabis consumption.
    - netizen-936824 5y ago
teejmya 5y ago
Thank you for posting what I wasn’t going to, because I’m in the same boat. Recent wedding, many people positive, I’m somehow not, and I was stoned the whole time. Anecdotal of course, but fascinating to think about. Stay safe y’all.
netizen-936824 5y ago
How does THC intoxication change social behaviors? Are you more or less social? Personally I doubt it was a direct pharmacological effect, but rather a secondary behavioral effect
- SuoDuanDao 5y ago
  If you're going to copypaste a statement saying you doubt it had a direct pharmacological effect on a post about a direct pharmacological effect, why not state what you think the issue with the study was?
  - netizen-936824 5y ago
    I'm not referencing the study, I'm talking about the comment that I'm replying to. The study is specifically about the acid versions of the compounds which are not psychoactive CBDA, THCA, and CBGA are all the carboxylic acid forms of the compound which is what is naturally produced by the cannabis plant. When we consume these, we make them psychoactive by heating. This turns them into CBD, THC, and CBG which are different compounds The non acids interact with proteins differently than the carboxylic acids. I'm saying that the people who say that they got stoned and this prevented COVID is highly unlikely and not at all related the the posted study at hand. Again: you don't get stoned off the compounds that were used in this COVID study. Full stop. This isn't even mentioning the fact that the concentrations of the carboxylic acid compounds used in the study are multiple orders of magnitude larger than what you can accomplish through smoking (micro vs nano-molar) PS. If you have an argument on why I might be incorrect I'm all ears, but down voting tells me nothing
    - SuoDuanDao 5y ago
      Fair enough as to your objections to linking these anecdotal effects to the study, though it's not the only of its kind and others point to actual CBD as a suspected mechanism[1]. As to your getting downvoted, the way you worded your objection you seemed to be implying the people you were responding to were pointing to THC as the mechanism. If you had been would have been strawmanning, medical uses of Cannabis are rarely about THC alone. [1] https://www.preprints.org/manuscript/202004.0315/v1?fbclid=IwAR2Yimux4U0XbQPd3l_OWEmcNMwlT3qHSVrwJhiqttCDYBMSDY9hkuXKnKo https://www.preprints.org/manuscript/202004.0315/v1?fbclid=I...
JPKab 5y ago
Amusing anecdote of my own: My wife and I are daily cannabis users. My wife far more than me. She uses it for chronic neuropathy caused by a genetic condition and has a medical card. We all caught COVID in February of 2021, before we were eligible for vaccination. I was the only one with any form of symptoms (loss my sense of smell) the rest were fully asymptomatic. My wife and I joked that maybe cannabis could be protective. Funny enough, I wasn't using much cannabis at all before the pandemic hit. I was 20 lbs heavier than I am now, and decided to start exercising rigorously to get as fit as possible with the expectation that a vaccine was 5 years out and we would all eventually contract the virus. I wanted to reduce my risk as much as possible. As part of my exercise habit, I would consume a 10mg THC/10mg CBD edible every night before going to the gym. I noticed it had bronchodilatory effects, and also made doing tons of cardio more fun on an emotional and mental level. All of this is anecdotal, and I have zero idea if the weed helped me or not. But I can say with certainty it helped me achieve a level of fitness and reduced body fat that almost certainly mitigated my COVID infection, based on the science around fitness/obesity and it's impact on severity.
hacknat 5y ago
Ditto. I'm a heavy(ish) user and I've never tested positive, despite being exposed more than once. Though admittedly I'm very cautious (always wear an N95, et al) and vaccinated.
- qwertox 5y ago
  I'm not a user and never tested positive. Though admittedly I'm very cautious (always wear an N95, et al) and vaccinated.
  - deleted 5y ago
    [deleted]
suifbwish 5y ago
This reminds me of the movie “a cabin in the woods” where the dude with the collapsible stainless steel baseball bat sized bong/coffee mug is rendered immune to the mind control gases by the cannabis he smokes constantly.

cbsks 5y ago

A year ago my wife got Covid. She isolated in our bedroom and I was quarantined in the rest of the house. I spent my time getting high and watching movies. I took multiple PCR tests and an antibody test and they were all negative. > It’s been of the few times in my life where my weed habit looks smart, and I’m loving every minute of it. Indeed :)

selectodude 5y ago

There were some early studies that showed that nicotine had a higher affinity for ACE2 than SARS-CoV-2 and that smokers had a lower risk of catching covid. I told everybody that while ripping my camels.

pille 5y ago
Worth repeating that this study was retracted. Authors failed to disclose a conflict of interest in their funding from the tobacco industry: https://erj.ersjournals.com/content/57/3/2002144 https://erj.ersjournals.com/content/57/3/2002144
- selectodude 5y ago
  In fairness, the study was retracted not due to the data but because "The European Respiratory Society, as a leading medical organisation in the respiratory field whose mission is to promote lung health and alleviate suffering from respiratory disease, has bylaws in place that do not permit individuals with ongoing relationships with the tobacco industry to participate in its activities" and in other situations, "The journal editors acknowledge that COPE (Committee on Publication Ethics) guidelines state that failure to disclose a potential conflict of interest is not normally sufficient grounds for retraction of a published article." I understand the journal's actions but I'd hesitate to say the study is wrong or has been retracted for anything beyond politics.
  - pille 5y ago
    I’m not sure what you mean by “politics” here, so I’d rather be explicit and say what it looks like to me. The tobacco industry has a rich history of trying to manipulate public opinion in their favor, and this article and authors’ undisclosed conflict of interest fits that pattern well: a study shows cigarettes are actually good for you in some way, and might even save you from the current pandemic; and then whoops, authors were getting paid by the tobacco industry, and then whoops again, they didn’t mention it when submitting for publication. If the study was retracted even though the CoPE guidelines don’t require a retraction, it implies to me that this case was more egregious than just some protocol mixup or forgetfulness. The most generous reading is that the retraction was made out of an abundance of caution and concern for the journal’s reputation. I suppose that’s possible, but I don’t see any further evidence in favor of exonerating the article, especially knowing the industry’s history.
    - selectodude 5y ago
      >I’m not sure what you mean by “politics” here, so I’d rather be explicit and say what it looks like to me. I mean that they explicitly said they retracted the study (in the journal, the authors haven't retracted anything) because they refuse to take any research from anybody who has ever accepted money from tobacco companies regardless of the rigor of the data or research. Non-academic reasons. I understand their stance because, as you said, the tobacco companies have a long sordid history of research and it's a journal of lung health with a strong "anti-smoking" bent, but calling the study "retracted" implies that it was somehow false or disproven when it has not been.
      - pille 5y ago
        > the authors haven't retracted anything Why would you trust the authors, though? They really should know better. To me, the omission is either the product of general incompetence (they forgot?), or intent to deceive. Both of those seem pretty disqualifying.
- 8bitsrule 5y ago
  Worth noting that this may or not have any bearing on the conclusions... "The manuscript presents some new data on, and provides a section of discussion of, the effect of tobacco consumption on patient susceptibility to COVID-19, and cites other studies that claim SARS-CoV-2 infection is less prevalent in smokers or tobacco users." Perhaps reading those other studies would be prejudicial. I once spend the better part of a day online looking for actual data on the known dangers of second-hand smoke. I found the not-so-surprising answers in a hard-to-find article in Lancet. It ... contradicted the mainstream tale.
  - pille 5y ago
    Could you share a link to this Lancet article?

diryawish 5y ago

I've noticed a correlation between heavy herb smokers and not getting the virus or having mild symptoms. People that primarily do hash haven't had the same benefit, which is kind of weird. This is all anecdotal.

netizen-936824 5y ago
How does THC intoxication change social behaviors? Are you more or less social? Personally I doubt it was a direct pharmacological effect, but rather a secondary behavioral effect
- dekhn 5y ago
  I'm a long-time THC consumer. The effects differ tremendously based on a wide range of variables. I've also retrained myself after many years to override my natural THC behaviors. Let me give some examples. College days, my first real year of smoking, I got really high. I mean, really really high. Close to a psychedelic experience. I went to the cafe to get an ice cream sundae and when I walked in, everybody in the entire room stared at me. Or, it felt like it. 30 people making eye contact looking at me AND THEY KNOW I'M HIGH. It was extremely uncomfortable- for my entire life growing up, I hadn't really ever made eye contact with people and having a lot of it was intense. A few years later, I get really high at a Grateful Dead show. Completely different experience- everybody was getting high and having a great time with strangers and I didn't feel judged and it was GREAT, socially speaking. Following college I began my professional career, but I am also a full time smoker, so I had to learn how to deal with the "OH GOD THEY KNOW" feelings and forced myself to be highly social at parties, etc. It can be really weird to be a person who is very introverted and wants nothing more to curl up in a ball far from people, but walk around a party introducing yourself to everybody and making intelligent conversation. Im interested in the psychopharmacology of cannabis and why so many people get the paranoia effect. I suspect it's probably a side effect of tweaking your endogenous cannabinoid system, in combination with the social pressures associated with cannabis consumption.
  - netizen-936824 5y ago

teejmya 5y ago

Thank you for posting what I wasn’t going to, because I’m in the same boat. Recent wedding, many people positive, I’m somehow not, and I was stoned the whole time. Anecdotal of course, but fascinating to think about. Stay safe y’all.

netizen-936824 5y ago

How does THC intoxication change social behaviors? Are you more or less social? Personally I doubt it was a direct pharmacological effect, but rather a secondary behavioral effect

SuoDuanDao 5y ago
If you're going to copypaste a statement saying you doubt it had a direct pharmacological effect on a post about a direct pharmacological effect, why not state what you think the issue with the study was?
- netizen-936824 5y ago
  I'm not referencing the study, I'm talking about the comment that I'm replying to. The study is specifically about the acid versions of the compounds which are not psychoactive CBDA, THCA, and CBGA are all the carboxylic acid forms of the compound which is what is naturally produced by the cannabis plant. When we consume these, we make them psychoactive by heating. This turns them into CBD, THC, and CBG which are different compounds The non acids interact with proteins differently than the carboxylic acids. I'm saying that the people who say that they got stoned and this prevented COVID is highly unlikely and not at all related the the posted study at hand. Again: you don't get stoned off the compounds that were used in this COVID study. Full stop. This isn't even mentioning the fact that the concentrations of the carboxylic acid compounds used in the study are multiple orders of magnitude larger than what you can accomplish through smoking (micro vs nano-molar) PS. If you have an argument on why I might be incorrect I'm all ears, but down voting tells me nothing
  - SuoDuanDao 5y ago
    Fair enough as to your objections to linking these anecdotal effects to the study, though it's not the only of its kind and others point to actual CBD as a suspected mechanism[1]. As to your getting downvoted, the way you worded your objection you seemed to be implying the people you were responding to were pointing to THC as the mechanism. If you had been would have been strawmanning, medical uses of Cannabis are rarely about THC alone. [1] https://www.preprints.org/manuscript/202004.0315/v1?fbclid=IwAR2Yimux4U0XbQPd3l_OWEmcNMwlT3qHSVrwJhiqttCDYBMSDY9hkuXKnKo https://www.preprints.org/manuscript/202004.0315/v1?fbclid=I...

JPKab 5y ago

Amusing anecdote of my own: My wife and I are daily cannabis users. My wife far more than me. She uses it for chronic neuropathy caused by a genetic condition and has a medical card. We all caught COVID in February of 2021, before we were eligible for vaccination. I was the only one with any form of symptoms (loss my sense of smell) the rest were fully asymptomatic. My wife and I joked that maybe cannabis could be protective. Funny enough, I wasn't using much cannabis at all before the pandemic hit. I was 20 lbs heavier than I am now, and decided to start exercising rigorously to get as fit as possible with the expectation that a vaccine was 5 years out and we would all eventually contract the virus. I wanted to reduce my risk as much as possible. As part of my exercise habit, I would consume a 10mg THC/10mg CBD edible every night before going to the gym. I noticed it had bronchodilatory effects, and also made doing tons of cardio more fun on an emotional and mental level. All of this is anecdotal, and I have zero idea if the weed helped me or not. But I can say with certainty it helped me achieve a level of fitness and reduced body fat that almost certainly mitigated my COVID infection, based on the science around fitness/obesity and it's impact on severity.

hacknat 5y ago

Ditto. I'm a heavy(ish) user and I've never tested positive, despite being exposed more than once. Though admittedly I'm very cautious (always wear an N95, et al) and vaccinated.

qwertox 5y ago
I'm not a user and never tested positive. Though admittedly I'm very cautious (always wear an N95, et al) and vaccinated.
- deleted 5y ago
  [deleted]

suifbwish 5y ago

This reminds me of the movie “a cabin in the woods” where the dude with the collapsible stainless steel baseball bat sized bong/coffee mug is rendered immune to the mind control gases by the cannabis he smokes constantly.