4 ms·

Many of the first infected in SA previously had Delta. I haven’t seen anyone suggesting that contracting Omicron gives you natural immunity to Delta. Here are

by awb 5y ago

Many of the first infected in SA previously had Delta. I haven’t seen anyone suggesting that contracting Omicron gives you natural immunity to Delta. Here are some links saying you can get both: https://www.inquirer.com/health/coronavirus/omicron-delta-endemic-milder-symptoms-20220104.html https://www.inquirer.com/health/coronavirus/omicron-delta-en... https://www.express.co.uk/life-style/health/1543522/can-you-get-omicron-after-delta-covid-variant-evg https://www.express.co.uk/life-style/health/1543522/can-you-... https://www.miamiherald.com/news/coronavirus/article256786862.html https://www.miamiherald.com/news/coronavirus/article25678686...

nradov 5y ago
You can get infected with both, but there is still a significant level of cellular immunity across all common variants. https://www.biorxiv.org/content/10.1101/2021.12.06.471446v1 https://www.biorxiv.org/content/10.1101/2021.12.06.471446v1
- awb 5y ago
  For someone not well versed in virology, can you please explain what that means? How do you get infected with significant levels of cellular immunity? And does that mean the infection is less severe?
  - nradov 5y ago
    There are multiple components to the immune system. For some viruses like measles, prior infection or vaccination usually triggers production of sterilizing antibodies which block subsequent infections in most patients. That isn't really the case for COVID-19. However the immune system also contains memory cells which can ramp up defenses more quickly during reinfections. The targets for those defenses are mostly the same across all SARS-CoV-2 variants. I have oversimplified this explanation to keep the comment short. If you'd like to really understand what's going on I recommend this panel discussion by a group of leading physicians; it's long but worth a listen. https://youtu.be/GklHGYY8vN8 https://youtu.be/GklHGYY8vN8
bagacrap 5y ago
if natural immunity derived from omicron doesn't protect you against Delta then why is there no more Delta in Colorado (as per TFA)?

by awb 5y ago

nradov 5y ago

You can get infected with both, but there is still a significant level of cellular immunity across all common variants. https://www.biorxiv.org/content/10.1101/2021.12.06.471446v1 https://www.biorxiv.org/content/10.1101/2021.12.06.471446v1

awb 5y ago
For someone not well versed in virology, can you please explain what that means? How do you get infected with significant levels of cellular immunity? And does that mean the infection is less severe?
- nradov 5y ago
  There are multiple components to the immune system. For some viruses like measles, prior infection or vaccination usually triggers production of sterilizing antibodies which block subsequent infections in most patients. That isn't really the case for COVID-19. However the immune system also contains memory cells which can ramp up defenses more quickly during reinfections. The targets for those defenses are mostly the same across all SARS-CoV-2 variants. I have oversimplified this explanation to keep the comment short. If you'd like to really understand what's going on I recommend this panel discussion by a group of leading physicians; it's long but worth a listen. https://youtu.be/GklHGYY8vN8 https://youtu.be/GklHGYY8vN8

bagacrap 5y ago

if natural immunity derived from omicron doesn't protect you against Delta then why is there no more Delta in Colorado (as per TFA)?