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> The remaining 29 participants acted as the control group and received a placebo, also with psychological support. How do you do placebo with psychedelics? Do
by j4hdufd8 5y ago
> The remaining 29 participants acted as the control group and received a placebo, also with psychological support.
How do you do placebo with psychedelics? Doesn't it quickly become obvious that you are tripping (or not)?
- ThePowerOfFuet 5y agoTypically they receive something like methylphenidate, and they are psilocybin-naïve so they don't know which they got.
- _moof 5y agohttps://en.wikipedia.org/wiki/Active_placebo https://en.wikipedia.org/wiki/Active_placebo
- 542458 5y agoDumb Question: How would you know that you're not just measuring that detrimental effects are identical across both substances?
- dasv 5y agoI have read that niacin is used as a placebo, it has a very noticeable physical effect but no psychedelic properties.
- skrtskrt 5y agoyou can gain psilocybin benefits without taking enough of it to trip
- ruined 5y agoshort answer, no. longer answer, dose-response varies, subjects don't necessarily know what the effects should be, or may not be able to identify the experience, and also it's pretty easy to get yourself into an autocthonous psychedelic headspace, especially if you expect "something" to happen
- Rastonbury 5y agoIt's obvious, I've participated in a such a study (not psilocybin). It has to be done though
- letitbeirie 5y agoI wonder if the control group being disappointed they're not tripping has any effect on these kinds of studies