4 ms·

Not just pfizer, everything, MABS and including previous infection too https://www.nature.com/articles/d41586-021-03796-6 https://www.nature.com/articles/d4158

by ck2 5y ago

Not just pfizer, everything, MABS and including previous infection too https://www.nature.com/articles/d41586-021-03796-6 https://www.nature.com/articles/d41586-021-03796-6 https://www.nature.com/articles/d41586-021-03826-3 https://www.nature.com/articles/d41586-021-03826-3 https://www.medrxiv.org/content/10.1101/2021.12.22.21268021 https://www.medrxiv.org/content/10.1101/2021.12.22.21268021 The question is if you get omicron can you then turn around and get delta which is still out there, just being out-competed at the moment.

throwaway55421 5y ago
Wouldn't the fact that it's outcompeting Delta imply that there is some cross immunity? I suppose there's some limited displacement effect e.g. if you have Omicron and self isolate you can't catch Delta during your self isolation period?
- mlyle 5y ago
  > Doesn't the fact that it's outcompeting Delta imply that there is some cross immunity? Not really. If Delta's Rt is greatly reduced because lots of people have immunity, Omicron can show up with a much higher Rt and grow in case numbers. It doesn't need to further reduce Delta's Rt to "win". I.e. even if R0 among those naive to the variants is similar, once you have 2/3rds of people who can't get Delta because of vaccination or prior infection and that can get Omicron, ... Omicron is going to win. And it looks like Omicron may be more contagious than Delta at baseline, so it's even quicker.
  - throwaway55421 5y ago
    Yes, sorry, that's not what I thought "outcompeting" meant in the epidemiological sense. I thought it implied that one variant grows to the detriment of the other. Otherwise, we could say something like "COVID outcompetes the flu". I don't think we have the data on Omicron vs Delta yet as you say.
    - mlyle 5y ago
      > Yes, sorry, that's not what I thought "outcompeting" meant in the epidemiological sense. I thought it implied that one variant grows to the detriment of the other. I mean, it does, but ... we don't really know that Omicron is outcompeting Delta in that sense. We know that Omicron case counts are growing, relative to Delta, but we don't know how well Omicron prevents later infection by Delta, etc. You asked "Wouldn't the fact that it's outcompeting Delta imply that there is some cross immunity?" The only fact that we have right now is that Omicron is growing quicker than Delta, not that Omicron is somehow suppressing Delta with cross-immunity. > Otherwise, we could say something like "COVID outcompetes the flu". Well--- COVID causing everyone to be careful, combined with influenza's lower Rt due to not being novel, really put a dent in influenza. So even then, without cross-immunity, you can have growth in one suppress growth in the other.
      - throwaway55421 5y ago
        Gotcha. yeah I agree on all of that.
- ck2 5y ago
  People making minimum aren't self-isolating, that food you ordered is being prepped and delivered by someone who went to work telling themselves "it's just a cold and they need that paycheck".
  - Supermancho 5y ago
    Afaict, you've completely missed the question embedded in the comment. You then reacted to the "isolated" keyword with some aimless statement. To restate simply: If you are infected with omicron and are isolated, can you be infected by Delta from say...a shoe that picked it up days ago? Answer: No, but that doesn't mean either disappear in the short term.
awb 5y ago
> The question is if you get omicron can you then turn around and get delta On Google, the top results seem to say that yes you can get both. But the data looks very preliminary. https://inews.co.uk/news/health/can-you-get-infected-omicron-more-than-once-reinfection-covid-variant-1369789 https://inews.co.uk/news/health/can-you-get-infected-omicron... > Can you get Omicron after previous infection with Delta? Yes. UK studies into Omicron have also suggested that previous Covid infection provides poor protection against the new strain. https://www.wxyz.com/news/health/ask-dr-nandi/can-you-get-infected-with-both-omicron-and-delta-at-the-same-time https://www.wxyz.com/news/health/ask-dr-nandi/can-you-get-in... > epidemiology experts have indicated that people could get infected with both delta and omicron together. We’ve seen co-infection before. Two studies — one in Brazil and one in France — have researched patients infected with two different strains of the virus at the same time. https://www.miamiherald.com/news/coronavirus/article256786862.html https://www.miamiherald.com/news/coronavirus/article25678686... > Already had COVID? You can still get infected with the omicron variant. https://whyy.org/articles/what-do-we-know-about-omicron-today/ https://whyy.org/articles/what-do-we-know-about-omicron-toda... > what was clear from that is people who have recovered from previous COVID-19 disease can get infected with omicron

by ck2 5y ago

throwaway55421 5y ago

Wouldn't the fact that it's outcompeting Delta imply that there is some cross immunity? I suppose there's some limited displacement effect e.g. if you have Omicron and self isolate you can't catch Delta during your self isolation period?

mlyle 5y ago
> Doesn't the fact that it's outcompeting Delta imply that there is some cross immunity? Not really. If Delta's Rt is greatly reduced because lots of people have immunity, Omicron can show up with a much higher Rt and grow in case numbers. It doesn't need to further reduce Delta's Rt to "win". I.e. even if R0 among those naive to the variants is similar, once you have 2/3rds of people who can't get Delta because of vaccination or prior infection and that can get Omicron, ... Omicron is going to win. And it looks like Omicron may be more contagious than Delta at baseline, so it's even quicker.
- throwaway55421 5y ago
  Yes, sorry, that's not what I thought "outcompeting" meant in the epidemiological sense. I thought it implied that one variant grows to the detriment of the other. Otherwise, we could say something like "COVID outcompetes the flu". I don't think we have the data on Omicron vs Delta yet as you say.
  - mlyle 5y ago
    > Yes, sorry, that's not what I thought "outcompeting" meant in the epidemiological sense. I thought it implied that one variant grows to the detriment of the other. I mean, it does, but ... we don't really know that Omicron is outcompeting Delta in that sense. We know that Omicron case counts are growing, relative to Delta, but we don't know how well Omicron prevents later infection by Delta, etc. You asked "Wouldn't the fact that it's outcompeting Delta imply that there is some cross immunity?" The only fact that we have right now is that Omicron is growing quicker than Delta, not that Omicron is somehow suppressing Delta with cross-immunity. > Otherwise, we could say something like "COVID outcompetes the flu". Well--- COVID causing everyone to be careful, combined with influenza's lower Rt due to not being novel, really put a dent in influenza. So even then, without cross-immunity, you can have growth in one suppress growth in the other.
    - throwaway55421 5y ago
      Gotcha. yeah I agree on all of that.
ck2 5y ago
People making minimum aren't self-isolating, that food you ordered is being prepped and delivered by someone who went to work telling themselves "it's just a cold and they need that paycheck".
- Supermancho 5y ago
  Afaict, you've completely missed the question embedded in the comment. You then reacted to the "isolated" keyword with some aimless statement. To restate simply: If you are infected with omicron and are isolated, can you be infected by Delta from say...a shoe that picked it up days ago? Answer: No, but that doesn't mean either disappear in the short term.

awb 5y ago

> The question is if you get omicron can you then turn around and get delta On Google, the top results seem to say that yes you can get both. But the data looks very preliminary. https://inews.co.uk/news/health/can-you-get-infected-omicron-more-than-once-reinfection-covid-variant-1369789 https://inews.co.uk/news/health/can-you-get-infected-omicron... > Can you get Omicron after previous infection with Delta? Yes. UK studies into Omicron have also suggested that previous Covid infection provides poor protection against the new strain. https://www.wxyz.com/news/health/ask-dr-nandi/can-you-get-infected-with-both-omicron-and-delta-at-the-same-time https://www.wxyz.com/news/health/ask-dr-nandi/can-you-get-in... > epidemiology experts have indicated that people could get infected with both delta and omicron together. We’ve seen co-infection before. Two studies — one in Brazil and one in France — have researched patients infected with two different strains of the virus at the same time. https://www.miamiherald.com/news/coronavirus/article256786862.html https://www.miamiherald.com/news/coronavirus/article25678686... > Already had COVID? You can still get infected with the omicron variant. https://whyy.org/articles/what-do-we-know-about-omicron-today/ https://whyy.org/articles/what-do-we-know-about-omicron-toda... > what was clear from that is people who have recovered from previous COVID-19 disease can get infected with omicron