Correct it is to help T-cells identify existing cancer cells, because current immunotherapy isn't all that great (cancer cells are tricky!). >> Next, the resea

Correct it is to help T-cells identify existing cancer cells, because current immunotherapy isn't all that great (cancer cells are tricky!). >> Next, the researchers employed new sequencing technology that makes a mRNA-based change of primary immune cells possible. They identified the target gene in single-cell RNA-sequencing datasets. Then they performed a functional test to validate the role of the target gene in enhanced immune cell-mediated killing of tumor cells. This is important because cancer cells have different properties that enable it to sneak past T-cells. So they are trying to identify specific characteristics to tumor cells that enable them to make mRNA that then is used to shape T-cell behavior. These vaccines can also be used (hopefully) to prevent metastasis, which is the true killer behind most cancers. Getting the body's immune system to respond is key. It could be seen as a prevention against spread in the body.