7 ms·
> "We have viable treatments that work and could be prescribed en masse. Not discussed, not mentioned." Can you explicitly mention what those treatments are? I
by lee 5y ago
> "We have viable treatments that work and could be prescribed en masse. Not discussed, not mentioned."
Can you explicitly mention what those treatments are? I'm genuinely curious.
- jacobolus 5y agoThere are various antiviral drugs which are orders of magnitude more expensive, have mediocre efficacy and a worse side effect profile compared to any of the main vaccines, and must be started within days of initial infection to work properly. They are a great addition (besides vaccines and non-pharmaceutical public health measures) for treating high-risk patients for whom the vaccines don’t provide perfect protection (e.g. the very elderly and immune compromised), but a poor primary response.
- landemva 5y agoIvermectin has anti-viral properties, has great multi-decade safety history, and is cheaper than a soda. It also has been shown to be an effective treatment when used early in disease.
- wux 5y agoThe Cochrane Reviews are regarded as one of the preeminent collections of systematic reviews in medicine. They conclude that “overall, the reliable evidence available does not support the use of ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials.” https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD... A similar conclusion regarding lack of evidence is discussed in NIH treatment guidelines: https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ivermectin/ https://www.covid19treatmentguidelines.nih.gov/therapies/ant... In line with consensus in the field, ivermectin is not contained among the treatment guidelines of any institution at which I have practiced.
- TheSpiceIsLife 5y agoThe Cochrane Collaboration can be safely disregarded by those who’s beliefs do not align with it’s reviews. <overly dramatic eye roll>
- pcwalton 5y agoWe just had an article about this. I am loath to link to Scott Alexander, but it's the most likely thing to persuade HN users. https://astralcodexten.substack.com/p/ivermectin-much-more-than-you-wanted https://astralcodexten.substack.com/p/ivermectin-much-more-t...
- stjohnswarts 5y agoIvermectin has been shown over and over to be no better than placebo. Sure it has it's uses but covid ain't one of them.
- thedream 5y agoSunlight, Vitamin D, turning off the TV
- passing_by_and 5y agoWe have excellent outcomes with monoclonal antibody-based drugs (the expensive route). Monoclonal is interesting because we may be able to take it preemptively. We have excellent results with steroids, vitamins, weight loss and exercise (low cost). One way to search (and ignore random people like myself) for this, is to look for different countries treatment protocols (they are often published into other languages). There is a lot of serious people working hard trying to find good solutions.
- m4rtink 5y agoThe anti-covid pill from Pfizer looks impressive: https://www.science.org/content/blog-post/pfizer-s-good-news-world-s-good-news https://www.science.org/content/blog-post/pfizer-s-good-news...
- SV_BubbleTime 5y agoI thought I remember reading something early on about protease inhibitors and COVID, cool to see that is coming out now.
- nradov 5y agoHere are the latest COVID-19 treatment guidelines. They are very effective in preventing deaths when applied early and aggressively. Unfortunately many patients wait too long before seeking care, and many physicians still don't follow the protocol. https://www.covid19treatmentguidelines.nih.gov/about-the-guidelines/whats-new/ https://www.covid19treatmentguidelines.nih.gov/about-the-gui...