5 ms·

The important bit: > Current research suggests that cannabis may negatively impact male fertility. Further studies are needed to validate that robust findings

by cmckn 5y ago

The important bit: > Current research suggests that cannabis may negatively impact male fertility. Further studies are needed to validate that robust findings in animal models will carry over into human experience. My takeaway: if you are having trouble reproducing, and/or your doctor finds some anomalies in a full fertility workup, you may want to talk about your marijuana use with them. That's about it.

zxcvbn4038 5y ago
I think this explains the sudden rush to legalize marijuana - if you can’t jail the pot heads then keep them from breeding! Solves multiple problems and so simple I’m surprised Nixon didn’t do this in the 70s.
- vmception 5y ago
  In most recreationally legal states, the legalization laws came from direct democracy with the people who would not be involved with any convoluted goal aside from the stated goal on the ballot. There is nothing a governor or representative could do. The people decided that jail was a counterproductive public policy measure and the people decided that the supply chain could be controlled to protect consumers. This concept will likely to be extended to most of the schedule, a new framework is necessary as prohibition is being repealed, again.
  - systemvoltage 5y ago
    Thanks for your comment. I used to think in conspiratorial ways - “Marijuana movement in US is a Chinese CCP weapon to kill US productivity, plummet the GDP and reduce population”. Sometimes it’s just easy to imagine that a bunch of people voted for it.
    - zxcvbn4038 5y ago
      China doesn't need to help, they just need to be patient while we do it to ourselves!
rusk 5y ago
> to our knowledge these results have not yet been replicated in human studies
- cmckn 5y ago
  Yup, this is just a literature review and there have been no human studies on this specific scenario.
- neonate 5y ago
  If you read that in context, it's clear that the qualification only applies to some of the results they're reporting: The strongest evidence of cannabis induced alterations in male fertility is in the category of semen parameters. Research supports a role for cannabis in reducing sperm count and concentration, inducing abnormalities in sperm morphology, reducing sperm motility and viability, and inhibiting capacitation and fertilizing capacity. Animal models demonstrate a role for cannabis in testicular atrophy, and reduced libido and sexual function but to our knowledge these results have not yet been replicated in human studies. "These results" clearly refers to the animal model studies they mention later, so that caveat does not apply to the "strongest evidence" they lead with, about sperm motility and viability, etc. At least not to judge by the abstract.
  - rusk 5y ago
    Yeah I saw that I was just highlighting the bit about animal studies. GP had the entire quote in context.
actually_a_dog 5y ago
> My takeaway: if you are having trouble reproducing, and/or your doctor finds some anomalies in a full fertility workup, you may want to talk about your marijuana use with them. That's about it. You should discuss all use of non-prescribed drugs with your doctor on a routine basis.
- cmckn 5y ago
  Absolutely; in my experience, they always ask (you probably won't have to be the one that brings it up). Healthcare is expensive, at least get your money's worth!
- 14 5y ago
  Do you not worry about buying life insurance and then asking for your medical history and then denying coverage or increased premiums?
  - OminousWeapons 5y ago
    Just because you discuss something with your doctor, doesn't mean that data needs to go into the EHR.
    - hellisothers 5y ago
      On the contrary you should assume it does unless you explicitly ask otherwise and even then it still might. And the OP is right, when you ask for life insurance they get everything because you have to allow them to ask for all data as if the request were coming from you.
      - OminousWeapons 5y ago
        Yes, what I was insinuating is that you should talk to your doctor about keeping occasional drug use out of the EHR before revealing any data.
        5y ago
keyle 5y ago
Are we really doping animals to find out that potheads can't reproduce as easily? To what benefit?
- xcambar 5y ago
  Medical and therapeutic marijuana has a wide range of benefits, from depression to Parkinson to glaucoma. Since your understanding of marijuana usage seems limited to recreational usage and you pejoratively call the consumers "potheads", I'd suggest you turn to the scientific literature, conclusively applied as policy in a growing number of countries, and confront your views to what you'd read.
- dumbfoundded 5y ago
  To be frank, you sound pretty ignorant with this comment. I'm sure you didn't intend such but any modern perspective puts weed as a safer alternative to alcohol and a social indulgence used by many extremely successful people. This also ignores all of the medical uses which alone make it worth studying.

by cmckn 5y ago

zxcvbn4038 5y ago

I think this explains the sudden rush to legalize marijuana - if you can’t jail the pot heads then keep them from breeding! Solves multiple problems and so simple I’m surprised Nixon didn’t do this in the 70s.

vmception 5y ago
In most recreationally legal states, the legalization laws came from direct democracy with the people who would not be involved with any convoluted goal aside from the stated goal on the ballot. There is nothing a governor or representative could do. The people decided that jail was a counterproductive public policy measure and the people decided that the supply chain could be controlled to protect consumers. This concept will likely to be extended to most of the schedule, a new framework is necessary as prohibition is being repealed, again.
- systemvoltage 5y ago
  Thanks for your comment. I used to think in conspiratorial ways - “Marijuana movement in US is a Chinese CCP weapon to kill US productivity, plummet the GDP and reduce population”. Sometimes it’s just easy to imagine that a bunch of people voted for it.
  - zxcvbn4038 5y ago
    China doesn't need to help, they just need to be patient while we do it to ourselves!

rusk 5y ago

> to our knowledge these results have not yet been replicated in human studies

cmckn 5y ago
Yup, this is just a literature review and there have been no human studies on this specific scenario.
neonate 5y ago
If you read that in context, it's clear that the qualification only applies to some of the results they're reporting: The strongest evidence of cannabis induced alterations in male fertility is in the category of semen parameters. Research supports a role for cannabis in reducing sperm count and concentration, inducing abnormalities in sperm morphology, reducing sperm motility and viability, and inhibiting capacitation and fertilizing capacity. Animal models demonstrate a role for cannabis in testicular atrophy, and reduced libido and sexual function but to our knowledge these results have not yet been replicated in human studies. "These results" clearly refers to the animal model studies they mention later, so that caveat does not apply to the "strongest evidence" they lead with, about sperm motility and viability, etc. At least not to judge by the abstract.
- rusk 5y ago
  Yeah I saw that I was just highlighting the bit about animal studies. GP had the entire quote in context.

actually_a_dog 5y ago

> My takeaway: if you are having trouble reproducing, and/or your doctor finds some anomalies in a full fertility workup, you may want to talk about your marijuana use with them. That's about it. You should discuss all use of non-prescribed drugs with your doctor on a routine basis.

cmckn 5y ago
Absolutely; in my experience, they always ask (you probably won't have to be the one that brings it up). Healthcare is expensive, at least get your money's worth!
14 5y ago
Do you not worry about buying life insurance and then asking for your medical history and then denying coverage or increased premiums?
- OminousWeapons 5y ago
  Just because you discuss something with your doctor, doesn't mean that data needs to go into the EHR.
  - hellisothers 5y ago
    On the contrary you should assume it does unless you explicitly ask otherwise and even then it still might. And the OP is right, when you ask for life insurance they get everything because you have to allow them to ask for all data as if the request were coming from you.
    - OminousWeapons 5y ago
      Yes, what I was insinuating is that you should talk to your doctor about keeping occasional drug use out of the EHR before revealing any data.
      - 5y ago

keyle 5y ago

Are we really doping animals to find out that potheads can't reproduce as easily? To what benefit?

xcambar 5y ago
Medical and therapeutic marijuana has a wide range of benefits, from depression to Parkinson to glaucoma. Since your understanding of marijuana usage seems limited to recreational usage and you pejoratively call the consumers "potheads", I'd suggest you turn to the scientific literature, conclusively applied as policy in a growing number of countries, and confront your views to what you'd read.
dumbfoundded 5y ago
To be frank, you sound pretty ignorant with this comment. I'm sure you didn't intend such but any modern perspective puts weed as a safer alternative to alcohol and a social indulgence used by many extremely successful people. This also ignores all of the medical uses which alone make it worth studying.