3 ms·

So here’s my logic but sounds a bit different than yours… While vaccinated people can be infected, the rate of infection is significantly reduced and therefore

So here’s my logic but sounds a bit different than yours… While vaccinated people can be infected, the rate of infection is significantly reduced and therefore fewer opportunities for the virus to mutate. But if the primary originator of variants are immunocompromised people then this wouldn’t be such a benefit. Fundamentally, very viral replication has a similar probability of a mutation happening and so therefore (it seems to me) that immunocompromised people are only more likely to generate new variants bc their infections last so much longer. Is this correct?

nradov 5y ago
The reduction in rate of infection for vaccinated people is limited and temporary. Over the long run vaccination will not significantly reduce opportunities for the virus to mutate. The real benefit of vaccination is reducing the risk of severe symptoms. https://www.nature.com/articles/d41586-021-02689-y https://www.nature.com/articles/d41586-021-02689-y Yes infections do tend to persist longer in immunocompromised patients with more total viral replication events over time and thus greater chance of a successful mutation. In addition there may be greater odds of recombination due to simultaneous infection with multiple strains, however that's somewhat speculative and I don't think it has been definitively detected. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220957/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220957/