4 ms·
The difficulty is that the immune system is not linear. I am far from being an expert, but terms like ADE and original antigenic sin are part of the literature.
by angelzen 5y ago
The difficulty is that the immune system is not linear. I am far from being an expert, but terms like ADE and original antigenic sin are part of the literature. This is not to say which approach is better, it is only a caveat that thinking in additive terms is just an approximation.
- pfisherman 5y agoPeople were worried about something like a dengue fever effect before we knew much about COVID. But now we have tons of data on breakthrough infections and and reinfections and it all says that immunity acquired via vaccine or prior exposure to the virus drastically reduces the risk of hospitalization or death in the case of a new infection.