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Given the... possible... origins of this virus, I hope they are being exceedingly careful about actually synthesizing a virus with all of these mutations at onc

Given the... possible... origins of this virus, I hope they are being exceedingly careful about actually synthesizing a virus with all of these mutations at once. Or they stand a very high risk of creating and releasing the doomsday variant they are worried about in the first place...

kmeisthax 5y ago
I think they only synthesized the spike proteins, not the whole virus. You don't need a whole virus to check if a protein is neutralized or not. (For the record, if spike proteins were themselves in any way harmful to life on their own, Moderna and Pfizer wouldn't be the primary vaccine vendors for the US right now.)
- nomel 5y ago
  > in any way harmful to life on their own I think it's fairly well accepted that they can cause myocarditis [1], which has killed some [2]. Better than getting the virus, but they appear to be capable of harm. I've naively wondered if the young men are getting jabbed in veins, rather than muscle tissue. 1. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/myocarditis.html https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/my... 2. https://www.bbc.com/news/world-asia-58380867 https://www.bbc.com/news/world-asia-58380867
  - nomel 5y ago
    No need to downvote. I'm not anti-vax, but I'm also not anti-science. The virologist, Vincent Racaniello, has a great podcast on YouTube. He has talked about this a few times. From my understanding of what he said, the spike protein created by infection, and with the vaccines, can "bind" proteins together, causing the myocarditis. There's speculation that this might be related to some of the cognitive problems of coronavirus, also. Approval doesn't mean absolute safety, since that's absolutely impossible to achieve. This is considered acceptable (as shown by the CDC page listing it as a risk), since an actual infection is worse, for most.

kmeisthax 5y ago

I think they only synthesized the spike proteins, not the whole virus. You don't need a whole virus to check if a protein is neutralized or not. (For the record, if spike proteins were themselves in any way harmful to life on their own, Moderna and Pfizer wouldn't be the primary vaccine vendors for the US right now.)

nomel 5y ago
> in any way harmful to life on their own I think it's fairly well accepted that they can cause myocarditis [1], which has killed some [2]. Better than getting the virus, but they appear to be capable of harm. I've naively wondered if the young men are getting jabbed in veins, rather than muscle tissue. 1. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/myocarditis.html https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/my... 2. https://www.bbc.com/news/world-asia-58380867 https://www.bbc.com/news/world-asia-58380867
- nomel 5y ago
  No need to downvote. I'm not anti-vax, but I'm also not anti-science. The virologist, Vincent Racaniello, has a great podcast on YouTube. He has talked about this a few times. From my understanding of what he said, the spike protein created by infection, and with the vaccines, can "bind" proteins together, causing the myocarditis. There's speculation that this might be related to some of the cognitive problems of coronavirus, also. Approval doesn't mean absolute safety, since that's absolutely impossible to achieve. This is considered acceptable (as shown by the CDC page listing it as a risk), since an actual infection is worse, for most.