7 ms·
Purely anecdotal but my loss of taste,smell came nearly two days after the primary COVID-19 symptoms had passed; making me wonder about the role immune response
by JRKrause 5y ago
Purely anecdotal but my loss of taste,smell came nearly two days after the primary COVID-19 symptoms had passed; making me wonder about the role immune response played into those apparent after-effects. Tangentially related, an acquaintance of mine (62+, history of lung disease) had lung failure leading to lung transplant following their vaccination. Causation is clearly not guaranteed here but I am still left to speculate about the role of the immune system in these outcomes.
- erickhill 5y agoI'm the only person I know that had an adverse reaction to my 2nd dose (Moderna). About 2 weeks after the shot I had 2 weeks of 1-2 degree daily fevers and fatigue with no other symptoms. My docs made me take 2 separate covid tests across that time - both were negative. During the end of the fevers I developed tinnitus in one ear. I'm under the strong impression right now that the tinnitus will never go away. Thankfully mine is not a tone but a constant humming, like a dishwasher or refrigerator. But yeah, something weird can occasionally occur with a very small % of the population either from the disease or the protection. That being said one of my colleagues at work - fully vaxxed - was infected by an un-vaxxed family member at a family reunion. He passed it onto another fully vaxxed work colleague. Both were sick for about two weeks and one lost his taste of smell. That was months ago. He says it has returned but only by about 50%.
- ed_elliott_asc 5y agoRe being ill after being vaxxed - the vaccine doesn't stop you getting it, it reduces the risk of you dying from it. Likely, if they were really badly ill when vaxxed then they would have needed medical help, could have died.
- bxrxdx 5y agoTo be clear, it also reduces your risk of infection.
- jjtheblunt 5y agoIt reduces your risk of infection taking hold, rather than being cleared fast by exposure to the pre-primed immune response ready and waiting. macroscopically that can look like prevention of infection.
- rdtsc 5y agoWould one know to get tested if they didn't have symptoms?
- woofie11 5y agoIncreasingly nominally. Right now, the protection is about 50%. I expect it will continue to fall as the virus evolves. 50% is a lot from a public health perspective -- there's a huge difference in the exponent -- but not something you can rely on to keep yourself or your relatives safe.
- borski 5y agoSo what you’re saying is: it reduces your risk of infection? :) I agree that it’s waning, and likely boosters will help, but it is far better (and safer) than doing nothing; just doesn’t preclude the need to mask up around unvaxed folks, etc.
- woofie11 5y agoIt doesn't preclude the need to mask up around vaxed folks either. Delta is spreading in part because vaxed folks stopped taking precautions, trusting in vaccines. That's not good for anyone. Vaxed folks won't get severe cases, but the jury is still out on long COVID. It also applies strong evolutionary pressure to vaccine-jumping mutations. Note: Before anyone jumps on the above statement, I'm not trying to imply anything else. Vaxed folks who don't take reasonable additional precautions ARE a major source of spread COVID19. That's not meant as a comparative statement (unvaxed folks are ALSO a major source of spread).
- borski 5y ago
- shadowgovt 5y ago> About 2 weeks after the shot I had 2 weeks of 1-2 degree daily fevers and fatigue with no other symptoms. My docs made me take 2 separate covid tests across that time - both were negative. And this is one of the maddening things about finding causality in disease. It might have been a reaction to the vaccine. Or you might have picked up an entirely unrelated illness on the same day as getting vaccinated... Because, for example, you had to stand in line with a handful of people and sit in the same chair as, perhaps, a couple hundred more, all of whom could have had God-knows-what. You probably didn't have COVID because two tests came back negative, but without knowing what else it could be, doctors don't know what test to try to find what you did have. Usually, if enough people report similar symptoms, the CDC would do outbreak follow-up with the testing site to see if something got brought in and spread widely.
- theslurmmustflo 5y agoI got tinnitus in both ears after first dose of Pfizer (got a very strong reaction in general, was feeling sick and weak for about 3 days after first shot). Been hesitant about getting the second because I don't want it to get worse. Interesting to read that I'm not the only one with this reaction. It's been 5 months now so I also assume that its permanent.
- yumraj 5y agoOne person I know got high fever, 102-103F, after first Pfizer shot. No side effects whatsoever after the second shot. So, it’s all over the place.
- _red 5y agoI caught covid in 2020. One of the strange effects was tinnitus in left ear. The strange thing is I started noticing the 'ringing' almost right at same time I dimly perceived I was getting sick, when things were still just at 'mild headache' level. I wonder if this is the work of spike protein causing some physical damage?
- aeternum 5y agoOne of the interesting mechanisms is that the spike proteins poke out of already infected cells and activate a calcium-ion channel which ultimately triggers infected cells to fuse together so you get these massive cells with 20 nuclei all producing more virus and fusing other cells. It seems like this mostly targets reparatory cells, but it's probably not great for hearing/smell if something similar happens to those cells. https://www.nature.com/articles/d41586-021-02039-y https://www.nature.com/articles/d41586-021-02039-y
- avalys 5y agoI also experienced tinnitus about two days after the second Pfizer dose. I had always had very mild tinnitus, noticeable only with specific attention in quiet rooms, and this was a clear increase that was noticeable in normal situations. I also had sensations of ear pressure and "fullness". Went to see an ENT who basically said "Yeah, maybe the vaccine, weird, but we know nothing here." and offered no solution. I had a hearing test which showed a slight decrease in sensitivity at low frequencies, but still in the clinical range for "normal hearing", so there wasn't really much to be done. In severe cases or those involving clear hearing loss, most people seem to think that oral steroids or steroid injections directly into the middle ear would be effective at reversing whatever inflammatory process is occurring and avoid long-term damage. Steroids have their own side effects, and to be effective, need to given as soon as possible. I had waited a bit to make the ENT appointment and didn't feel like my case was severe enough to ask for this. Now two months later the ear sensations have gone away and the tinnitus is back to the mild level I experienced previously. But it was an unpleasant experience that I do not wish to repeat. I will probably avoid the booster if possible. However, many people have also reported permanent hearing loss and tinnitus after contracting COVID. For all I know, getting the vaccine may have saved me from much more serious and long-lasting symptoms that would have come with an actual COVID infection. No way to know unfortunately. Goddamn biology. Back to coding now.
- ce4 5y agoIn my case it was an undiagnosed long dormant bacterial tick borne infection that periodically became active and became worse the last couple of years. Subsequent treatment resulted in a heavy spike of symptoms i had long forgotten I once had years ago or accepted as the "normal" state. Of almost all of those symptoms I was unaware they might be somehow connected, one of them being Tinnitus in the right ear. There are probably lots of low level infections that cause no to only mild symptoms for years. My first BioNtech/Pfizer shot also triggered it again and some other funny symptoms that lasted for more than three weeks. Second shot will be next week.
- double0jimb0 5y agoNext time try Flonase up the nose, much less invasive than a shot into the middle ear.
- cabalamat 5y agoI was stiff in my right leg the day after being vaccinated with AstraZeneca. I could hardly walk, although the effects wore off during the day.
- dystroy 5y agoYou're not alone. Acute tinnitus (making it hard to sleep) is the most important symptom in a range of problems (many looking like allergy ones) my wife got at her second dose of Moderna. It's still here 2 months after the injection. There are a few articles on the links between those vaccines and tinnitus but right now it doesn't look like a deeply studied problem, nor even one physicians are interested into.
- m0zg 5y ago> I'm the only person I know that had an adverse reaction to my 2nd dose (Moderna) I don't _personally_ know anyone who died from COVID. Yet people are clearly dying from it. They are also sometimes getting adverse reactions to vaccines, up to and including death. Personal anecdotes are not data, however, and it's annoying and alarming that COVID deaths are inflated (got run over by a bus, but had COVID that only shows up at 40 PCR cycles? you died "with covid"), whereas vaccine adverse effects are carefully swept under the rug. It is also extremely counterproductive if the goal is to persuade people to get vaccinated, and it demolishes what little trust in the authorities people still had. I wish responsible adults, and not political operatives (or former / future Big Pharma corporate board members), ran our health authorities such as the FDA and the CDC. PS: I'm vaccinated, obviously, since I'm not an idiot.
- chitowneats 5y agoCongratulations on pissing off every possible group with different parts of this comment. I upvoted you anyway.
- m0zg 5y agoIn the age of lies telling the truth is a revolutionary act. We're most certainly being had, and a crisis is being put to a good use by the interested parties: politicians, businesses, banks/hedge funds, and plain ol' facebook/twitter mouth breathers who vie for popularity and likes. Adults have left the room decades ago, as far as I can tell, if there were any adults in the public sector in the first place.
- curation 5y agoAgreed: moral acts are received as evil. We are attempting to 'save our democracy' and 'protect everyone' and that always only ends in one place: totalitarianism. The paradox of sustaining safety/risk is where we need to sit. But the coordination (blind and ideological; I don't think any of it is evil) of media wanting clicks, politicians being paid means we all serve The Economy. Thank you for your comments!
- 5y ago
- cafard 5y agoMany people I know felt rotten for the twenty-four hours after the 2nd Moderna dose, and I was one of them.
- strangus 5y agoThat's interesting, my buddy got tinnitus from the J&J shot.
- yryan 5y agoI also developed Tinnitus after the J&J shot. Both ears. The ringing was on and off for the first few weeks after the vaccine shot but at about 4-5 weeks was a full fledged in both ears. Was so loud at first I couldn't focus on anything because of the anxiety. I'm either used to it now or it's quieted down enough that I can at least get through my day. An ENT didn't help me out besides prescribing something that's typically used for insomniacs so that I can sleep at night.
- xxpor 5y agoIn the flu pandemic of 1918, the group it was most dangerous for was the inversion of covid (and normal flu): healthy young people. Our best guess for why this is is that was because it caused a cytokine storm, which is basically an autoimmune response where the body ends up killing itself because the immune system goes way overboard. Unfortunately while the general idea of cytokine storms had been floating around for quite a while, it wasn't named until 1993, and wasn't really studied as its own thing until 2002/2003. No chance they would have been able to do anything about it in 1918.
- nielsbot 5y agoI read recently this might be linked to people who were exposed to the 1889 flu pandemic. https://www.smithsonianmag.com/history/why-did-1918-flu-kill-so-many-otherwise-healthy-young-adults-180967178/ https://www.smithsonianmag.com/history/why-did-1918-flu-kill...
- nradov 5y agoMaybe, maybe not. There is growing evidence that the 1889 pandemic wasn't caused by influenza at all but rather by another coronavirus. https://ec.europa.eu/research-and-innovation/en/horizon-magazine/qa-why-history-suggests-covid-19-here-stay https://ec.europa.eu/research-and-innovation/en/horizon-maga...
- InitialLastName 5y agoMy understanding of the cause behind the longer-term loss of smell and taste is that it is related to damage to the cells that support your nerve cells. The nerve cells can function for some amount of time without that support, but will eventually start to die off, which causes the sensory loss. This suggests that the symptom could still be caused by damage from the infection, just in a way that has the potential to be a lagging indicator.
- curation 5y agoI've had such bad sinusitis that I've lost my sense of smell thus taste for months at a time. It came back slowly but it was awful. The treatment I use now is nasal cortosteroids to prevent an oncoming attack. But I do not dare suggest anything of course, considering.
- teddyh 5y agoYour comment has attracted a host of comments containing personal anecdotes from various people having different adverse experiences with different COVID-19 vaccines. What purpose do these comments (and yours) serve, except to divert attention away from science and towards personal anecdotes and rumor?
- deleted 5y ago[deleted]
- lrem 5y agoPeople like to share their experiences. Sharing them with people who experienced similar things gives that warm fuzzy feeling of community. One that we're not getting enough due to the pandemics.
- MatteoFrigo 5y agoA result is scientific not when experiments confirm it, but only when repeated attempts at disproving it all fail. Without the skeptics, the crackpots, the deniers, there is no science. When vaccines are concerned, the skeptics have been censored and ostracized (generally speaking, not on HN). Therefore, whatever results are claimed to be science are not such, or at least not yet. Relying on anecdotes is the only recourse that we have to restore some semblance of scientific process.
- dalmo3 5y agoThe science is there to affect/improve/save people's lives. Those comments are talking about people's lives.
- secondaryacct 5y agoWe should just be assigned numbers and allowed one pre proposed sentence by HN topic. Here "Science is great, keep up the good work". I live in China, where we do that. You re welcome to join, something tells me you'll like it here.
- stordoff 5y agoCovid-19 symptoms coming in two waves is something I've heard from a few people, and anecdotally fits my experience - generic symptoms (body aches, fatigue, fever) cleared up, then about a day later my blood oxygen levels dropped sharply with no obvious symptoms (happy hypoxia). I wonder what causes this apparent pattern. I had a positive PCR test during the first set of symptoms FWIW.
- refurb 5y agoI hope anyone who has an adverse event related to a vaccine reports it to Health and Human Services (if you're in the US) or your respective gov't agency. https://vaers.hhs.gov/reportevent.html https://vaers.hhs.gov/reportevent.html Patients can report adverse events. Even suspected adverse events can/should be reported. This is how rare side effects can be identified and evaluated. A single report of tinnitus is unlikely to be flagged, but 10,000 reports? Absolutely.