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Can someone with a better understanding talk about the specifics of how/why a vaccine like this might end up not being effective against HIV (i.e. what makes HI
by elromulous 5y ago
Can someone with a better understanding talk about the specifics of how/why a vaccine like this might end up not being effective against HIV (i.e. what makes HIV so good at evading our efforts)? I suspect we've been in this boat many times in the past 40 years: a promising cure is just around the corner.
- vibrio 5y agoTwo half-baked comments off the top of my head: -HIV targets, infects and cripples the immune system. While CoV2 infects and replicated aggressively, causing inflammation and fibrosis, HIV goes in, gets a foothold, hides and lingers like an insurgent, slowly exhausting the immune system. Very different approaches and how they are impacted by vaccines may be very different. -Convincing people to take the vaccine would be hard. Look how hard it is with a respiratory pandemic. It's "easy" to be non-high risk for HIV and people probably believe they can't get it, but people seem to continue getting it.