4 ms·
Thanks for pointing that out and doing the math. I did some digging, here is the paper outlining the methods and data sources for the numbers on the page you l
by criticaltinker 5y ago
Thanks for pointing that out and doing the math.
I did some digging, here is the paper outlining the methods and data sources for the numbers on the page you linked to [1]. That paper cites two other papers used to estimate the asymptomatic proportion [2][3].
Here is a more recent systematic review [4], which estimates that at least 33% of infections are asymptomatic.
And another recent paper which estimates the lower bound for asymptomatic proportion (AP) to be 37%, with an upper bound of 67% [5]. "The estimated AP varied with age, from 74% (95% CI 65–90%) for < 20 years, to 61% (95% CI 57–65%) for the 50–59 years age-group." [5]
[1] Estimated Incidence of Coronavirus Disease 2019 (COVID-19) Illness and Hospitalization—United States, February–September 2020
https://academic.oup.com/cid/article/72/12/e1010/6000389 https://academic.oup.com/cid/article/72/12/e1010/6000389
[2] Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: Systematic review and meta-analysis
https://jammi.utpjournals.press/doi/pdf/10.3138/jammi-2020-0030 https://jammi.utpjournals.press/doi/pdf/10.3138/jammi-2020-0...
[3] Age-dependent effects in the transmission and control of COVID-19 epidemics
https://www.nature.com/articles/s41591-020-0962-9 https://www.nature.com/articles/s41591-020-0962-9
[4] The Proportion of SARS-CoV-2 Infections That Are Asymptomatic
https://www.acpjournals.org/doi/full/10.7326/M20-6976 https://www.acpjournals.org/doi/full/10.7326/M20-6976
[5] Estimating the asymptomatic proportion of SARS-CoV-2 infection in the general population: Analysis of nationwide serosurvey data in the Netherlands
https://link.springer.com/article/10.1007/s10654-021-00768-y https://link.springer.com/article/10.1007/s10654-021-00768-y
- nradov 5y agoAsymptomatic is kind of a fuzzy concept so the numbers will vary based on methodology. If you test positive and then have a bit of diarrhea one day is that a COVID-19 symptom or the consequences of a bad burrito? In mild cases there's no way to be sure. https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/s...
- criticaltinker 5y agoI agree there can be many confounding factors. To clarify your point: this leads you to the conclusion that the asymptomatic proportion is likely under-estimated? And conversely, the symptomatic proportion is likely over-estimated?