4 ms·

CDC document cites delta variant’s ability to spread among the vaccinated

14 points by tguvot 5y ago

tguvot 5y ago
Before somebody asks: https://archive.is/T23eV https://archive.is/T23eV
tguvot 5y ago
And the actual presentation https://context-cdn.washingtonpost.com/notes/prod/default/documents/8a726408-07bd-46bd-a945-3af0ae2f3c37/note/57c98604-3b54-44f0-8b44-b148d8f75165.#page=1 https://context-cdn.washingtonpost.com/notes/prod/default/do...
AndrewBissell 5y ago
> "It’s hard to do, but I think we have to become comfortable with coronavirus not going away.”
base698 5y ago
> The presentation highlights the daunting task the CDC faces. It must continue to emphasize the proven efficacy of the vaccines at preventing severe illness and death while acknowledging milder breakthrough infections may not be so rare after all, and that vaccinated individuals are transmitting the virus. The agency must move the goal posts of success in full public view.
unanswered 5y ago
> vaccination is now about personal protection — protecting oneself against severe disease. Herd immunity is not relevant So there is no real reason to force people to vaccinate now, if they don't want to? Leave them to their chosen fate.
landemva 5y ago
"Vaccinated people infected with delta have measurable viral loads similar to those who are unvaccinated and infected with the variant." I am interested in learning how people who had natural infections, and now the real antibodies, are faring. Particularly in the young who enjoy high recovery rates, maybe natural infection can reduce the spread of the new variant. I had it and recovered, so this applies to me.
- johntfella 5y ago
  I found the explanation of natural infection rather interesting in this piece however unfortunately I have not been able to find the original source: “Natural infection exposes us to all the proteins of the virus – not just one like the vaccine – leading to a wider response by the immune system. Even someone who has a low level of antibodies will be protected by T-lymphocytes, a cellular protection – and given this response directed at more viral proteins, new variants will have more difficulty entering the organism” (1). The quoted immunologist is on twitter and is relatively conventional (2). I have attempted to research this specific line some but because there is so much skewing with searches right now I haven't had too much luck. Suppose partially why I share it in comment form is I never felt it was of quality for a post submission eg.. it's not the original source. I do think if that quote is accurate then the issue of testing for t cells et al to determine whether someone has been infected prior to vaccination might be a good way to go especially if the concluding remarks by Camara et al hold true in that "the second BNT162b2 vaccine dose results in a reduction of cellular immunity in COVID-19 recovered individuals" (3). Both my brother and I have uc. My brother got the vaccination and developed a pretty bad flare up. My uc condition has always been a bit more severe than his. I know I have had the virus and even volunteered to help out months later when sister and her husband got sick and nothing developed on my end. Considering Akinosoglou et al hypothesis, "that, even though, COVID-19 vaccination does not provoke de novo immune mediated adverse events, it is possible that, the immunologic response triggers pre- existing underlying dysregulated pathways" (4), I have been wary of taking the vaccine with the additional knowledge that I had the natural infection. Luckily in that I am self employed and work from home, most of my shopping is done online even prior to the pandemic so I feel at least I'm well positioned to wait it out a bit longer until research down the road with less upfront bias emerges. 1. https://www.portugalresident.com/new-data-shows-natural-covid-infection-leaves-people-better-protected-than-if-they-take-the-vaccine/ https://www.portugalresident.com/new-data-shows-natural-covi... 2. https://twitter.com/lgraca https://twitter.com/lgraca 3. https://doi.org/10.1101/2021.03.22.436441 https://doi.org/10.1101/2021.03.22.436441 4. https://doi.org/10.1016/j.clim.2021.108721 https://doi.org/10.1016/j.clim.2021.108721
  - AndrewBissell 5y ago

14 points by tguvot 5y ago

Before somebody asks: https://archive.is/T23eV https://archive.is/T23eV

And the actual presentation https://context-cdn.washingtonpost.com/notes/prod/default/documents/8a726408-07bd-46bd-a945-3af0ae2f3c37/note/57c98604-3b54-44f0-8b44-b148d8f75165.#page=1 https://context-cdn.washingtonpost.com/notes/prod/default/do...

AndrewBissell 5y ago

> "It’s hard to do, but I think we have to become comfortable with coronavirus not going away.”

base698 5y ago

> The presentation highlights the daunting task the CDC faces. It must continue to emphasize the proven efficacy of the vaccines at preventing severe illness and death while acknowledging milder breakthrough infections may not be so rare after all, and that vaccinated individuals are transmitting the virus. The agency must move the goal posts of success in full public view.

unanswered 5y ago

> vaccination is now about personal protection — protecting oneself against severe disease. Herd immunity is not relevant So there is no real reason to force people to vaccinate now, if they don't want to? Leave them to their chosen fate.

landemva 5y ago

"Vaccinated people infected with delta have measurable viral loads similar to those who are unvaccinated and infected with the variant." I am interested in learning how people who had natural infections, and now the real antibodies, are faring. Particularly in the young who enjoy high recovery rates, maybe natural infection can reduce the spread of the new variant. I had it and recovered, so this applies to me.

johntfella 5y ago
I found the explanation of natural infection rather interesting in this piece however unfortunately I have not been able to find the original source: “Natural infection exposes us to all the proteins of the virus – not just one like the vaccine – leading to a wider response by the immune system. Even someone who has a low level of antibodies will be protected by T-lymphocytes, a cellular protection – and given this response directed at more viral proteins, new variants will have more difficulty entering the organism” (1). The quoted immunologist is on twitter and is relatively conventional (2). I have attempted to research this specific line some but because there is so much skewing with searches right now I haven't had too much luck. Suppose partially why I share it in comment form is I never felt it was of quality for a post submission eg.. it's not the original source. I do think if that quote is accurate then the issue of testing for t cells et al to determine whether someone has been infected prior to vaccination might be a good way to go especially if the concluding remarks by Camara et al hold true in that "the second BNT162b2 vaccine dose results in a reduction of cellular immunity in COVID-19 recovered individuals" (3). Both my brother and I have uc. My brother got the vaccination and developed a pretty bad flare up. My uc condition has always been a bit more severe than his. I know I have had the virus and even volunteered to help out months later when sister and her husband got sick and nothing developed on my end. Considering Akinosoglou et al hypothesis, "that, even though, COVID-19 vaccination does not provoke de novo immune mediated adverse events, it is possible that, the immunologic response triggers pre- existing underlying dysregulated pathways" (4), I have been wary of taking the vaccine with the additional knowledge that I had the natural infection. Luckily in that I am self employed and work from home, most of my shopping is done online even prior to the pandemic so I feel at least I'm well positioned to wait it out a bit longer until research down the road with less upfront bias emerges. 1. https://www.portugalresident.com/new-data-shows-natural-covid-infection-leaves-people-better-protected-than-if-they-take-the-vaccine/ https://www.portugalresident.com/new-data-shows-natural-covi... 2. https://twitter.com/lgraca https://twitter.com/lgraca 3. https://doi.org/10.1101/2021.03.22.436441 https://doi.org/10.1101/2021.03.22.436441 4. https://doi.org/10.1016/j.clim.2021.108721 https://doi.org/10.1016/j.clim.2021.108721
- AndrewBissell 5y ago