2 ms·
An importing distinction: The author did not get himself sequenced. He had genotyping. Genotyping basically picks out a few specific data points. Sequencing re
by ineedasername 6y ago
An importing distinction: The author did not get himself sequenced. He had genotyping.
Genotyping basically picks out a few specific data points. Sequencing reads an entire piece or entire genome completely.
From a health perspective, genotyping pulls data points that we already know can be markers for something significant. Sequencing gets a lot more data, and would sort of be "future proof" against the need to do further testing if new markers were identified you can just look at the data already gathered. Otherwise you'd need to get Genotyping done again.
- souradip 6y agoThis is very true, and genotyping just the HLA/KIR loci won't tell you much about all the other genes that are important for health. However, the HLA typing is at least a start (and a free byproduct of signing up to donate stem cells) to introduce you to the rabbit hole of personal genomics! :) This is also slightly different to the (linkage-disequilibrium-based) SNP arraying done by other genotyping places, since the HLA locus is fairly widely researched in its associations with infection and (auto)immunity!
- ineedasername 6y agoOh absolutely... It's a lot more expensive for sequencing, so there's no reason not to take a cheap option that at least gets you checked against known issues.