4 ms·
You're making so many assumptions in your posts. Yes, to do a proper RCT you need to confine and monitor subjects in a controlled environment. YOU used the wor
by serverholic 5y ago
You're making so many assumptions in your posts.
Yes, to do a proper RCT you need to confine and monitor subjects in a controlled environment. YOU used the word "years" and nobody ever suggested a study that long. If you're implying that you need a study that long to gather meaningful results then that's just simply not true.
Let me put this plainly, you can design RCTs that are:
A) Safe for participants.
B) Aren't too long.
C) Don't rely on subject reported data.
D) Still give meaningful results.
These are not mutually exclusive and they are done all the time. These are gold-standard experiments in the nutrition field.
Like you said, they are expensive to do and usually only have a small number of subjects. That's why I'm suggesting that wealthy governments should collaborate to fund massive-scale trials at maximum quality.
- nradov 5y agoIn the general case "B" and "D" are mutually exclusive. For the important questions in human nutrition like whether a diet high in saturated fat increases the risk of all cause mortality it takes many years for significant effects to appear.
- serverholic 5y agoThere are many useful things we have learned and can learn from shorter studies. Best of luck to you. I'm out.