That stone age artists were using mind-altering effects is a pretty easy ballpark guess. I think most hunter-gatherer societies involve hallucinogens of various

That stone age artists were using mind-altering effects is a pretty easy ballpark guess. I think most hunter-gatherer societies involve hallucinogens of various sorts in their religious ceremonies, the Romans and Greeks used a significant amount of drugs (the Oracle at Delphi was known for this) and Alcohol use was vastly larger at the time of the thirteen colonies. See: https://www.americanheritage.com/alcoholic-republic-american-tradition https://www.americanheritage.com/alcoholic-republic-american...