4 ms·

Your point probably stands, but COVID is not a respiratory disease. It's a vascular disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/ https://www.

Your point probably stands, but COVID is not a respiratory disease. It's a vascular disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556303/

TheSpiceIsLife 6y ago
What does SARS stand for? The article you linked, first paragraph: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to multi-system dysfunction with emerging evidence suggesting that SARS-CoV-2-mediated endothelial injury is an important effector of the virus. Potential therapies that address vascular system dysfunction and its sequelae may have an important role in treating SARS-CoV-2 infection and its long-lasting effects. You're saying it's not a respiratory disease? Are you sure?
- pmiller2 6y ago
  Yes, I'm sure. Continue reading, please.
  - peytn 6y ago
    Worth mentioning that one of the authors happens to be on the board of a biotech developing a stroke product.
  - TheSpiceIsLife 6y ago
    Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. But then again, if it's damaging the vascular system then it's also a kidney disease. 25% of each stroke volume out of the heart goes to the kidneys. Anything that damages the vascular system will strain the heart leading to higher blood pressure, which will damage the kidneys. Poor kidney clearance will increase the incidence of joint diseases like gout and arthritis. COVID-19 is a joint disease.
    - pmiller2 6y ago
      I'll be sure to notify the researchers to issue a correction. How may I credit you?
    - Zancarius 6y ago
      You know what structures also have ACE2 receptors that SARS-CoV-2 attacks? The endothelial cells. Guess how SARS-CoV-2 causes the formation of emboli that fundamentally result in blocking the lung vasculature? By attacking the endothelium.
- Zancarius 6y ago
  It's largely called SARS-CoV-2 because, surprise, it's in the coronavirus family that causes SARS. Yes, it is a respiratory disease, but what we've learned in the last year is that the worst respiratory effects from this disease aren't from it infecting pneumocytes (that's how it spreads) but from the emboli that it creates which then block the vasculature of the lungs. I'd suggest this lecture by Dr. Seheult of MedCram which dates back to around the time we started discoverying the concerning underlying pathologies of the disease process: https://www.youtube.com/watch?v=PlUFibXtDxQ https://www.youtube.com/watch?v=PlUFibXtDxQ This is also one of the possible explanations for the appearances of rash-like lesions in the extremities of younger populations who are otherwise asymptomatic: Capillary vasculature becoming blocked by the formation of emboli creating a redness in the skin is another feature of a disease that is primarily vascular in nature. Not to mention the increased risk of stroke. The correct answer is that it's "kind of both" but that the damaging effects from SARS-CoV-2 are less a consequence of destruction of lung cells, as was originally thought, and more a function of blocking the vasculature that carry away oxygen.
nradov 6y ago
According to the CDC: "COVID-19 is a respiratory disease caused by SARS-CoV-2". So you can take your argument up with them. A disease can be more than one thing. https://www.cdc.gov/dotw/covid-19/index.html https://www.cdc.gov/dotw/covid-19/index.html
- deleted 6y ago
  [deleted]
- pmiller2 6y ago
  I'll get right on that.

TheSpiceIsLife 6y ago

What does SARS stand for? The article you linked, first paragraph: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to multi-system dysfunction with emerging evidence suggesting that SARS-CoV-2-mediated endothelial injury is an important effector of the virus. Potential therapies that address vascular system dysfunction and its sequelae may have an important role in treating SARS-CoV-2 infection and its long-lasting effects. You're saying it's not a respiratory disease? Are you sure?

pmiller2 6y ago
Yes, I'm sure. Continue reading, please.
- peytn 6y ago
  Worth mentioning that one of the authors happens to be on the board of a biotech developing a stroke product.
- TheSpiceIsLife 6y ago
  Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. But then again, if it's damaging the vascular system then it's also a kidney disease. 25% of each stroke volume out of the heart goes to the kidneys. Anything that damages the vascular system will strain the heart leading to higher blood pressure, which will damage the kidneys. Poor kidney clearance will increase the incidence of joint diseases like gout and arthritis. COVID-19 is a joint disease.
  - pmiller2 6y ago
    I'll be sure to notify the researchers to issue a correction. How may I credit you?
  - Zancarius 6y ago
    You know what structures also have ACE2 receptors that SARS-CoV-2 attacks? The endothelial cells. Guess how SARS-CoV-2 causes the formation of emboli that fundamentally result in blocking the lung vasculature? By attacking the endothelium.
Zancarius 6y ago
It's largely called SARS-CoV-2 because, surprise, it's in the coronavirus family that causes SARS. Yes, it is a respiratory disease, but what we've learned in the last year is that the worst respiratory effects from this disease aren't from it infecting pneumocytes (that's how it spreads) but from the emboli that it creates which then block the vasculature of the lungs. I'd suggest this lecture by Dr. Seheult of MedCram which dates back to around the time we started discoverying the concerning underlying pathologies of the disease process: https://www.youtube.com/watch?v=PlUFibXtDxQ https://www.youtube.com/watch?v=PlUFibXtDxQ This is also one of the possible explanations for the appearances of rash-like lesions in the extremities of younger populations who are otherwise asymptomatic: Capillary vasculature becoming blocked by the formation of emboli creating a redness in the skin is another feature of a disease that is primarily vascular in nature. Not to mention the increased risk of stroke. The correct answer is that it's "kind of both" but that the damaging effects from SARS-CoV-2 are less a consequence of destruction of lung cells, as was originally thought, and more a function of blocking the vasculature that carry away oxygen.

nradov 6y ago

According to the CDC: "COVID-19 is a respiratory disease caused by SARS-CoV-2". So you can take your argument up with them. A disease can be more than one thing. https://www.cdc.gov/dotw/covid-19/index.html https://www.cdc.gov/dotw/covid-19/index.html

deleted 6y ago
[deleted]
pmiller2 6y ago
I'll get right on that.