> New variants start popping up that are resistant to the previous version. There is no evidence that new variants have escaped natural immunity in any populat

> New variants start popping up that are resistant to the previous version. There is no evidence that new variants have escaped natural immunity in any population. To date, all of the known variants are neutralized by existing antibodies and immune sera. This is a fact -- we've seen effects on titers in a few papers, but nothing has yet to escape immunity. That said, immune escape is probably inevitable -- this virus mutates far too quickly and has too many zoonotic reservoirs to prevent that from happening. To the extent that this occurs, a mix of natural and vaccine-induced immunity is likely the fastest and most robust way to suppress the virus.