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I know these threads tend to get bogged down with the various things all COVID related threads do these days, but let's just take a second to savor this moment.

by Exmoor 6y ago

I know these threads tend to get bogged down with the various things all COVID related threads do these days, but let's just take a second to savor this moment. The mRNA vaccines were developed in days[0], using only the genetic sequence of the virus. Yes, testing took many months, but science solved what is typically the hard part of the problem overnight. Personally I'm hoping I get the mRNA vaccine not so much because they're currently the most effective, but because it will make me some small part of one of the most impactful scientific works of our lifetimes. We should be seeing another announcement in a week for the Moderna mRNA vaccine as well as their committee review is scheduled for 12/17. [0]https://nymag.com/intelligencer/2020/12/moderna-covid-19-vaccine-design.html https://nymag.com/intelligencer/2020/12/moderna-covid-19-vac...

redisman 6y ago
Pretty incredible and pretty surreal. I honestly wasn't sure how the utterly incompetent federal response of the US would ever dig itself out of this and I guess the answer is here.
akkawwakka 6y ago
It’s worth highlighting that a ton of basic science work went into mRNA vaccine development, starting in the early 1990s: - developing the lipid nanoparticles that the mRNA is delivered in, so your cells could actually take it up intact - figuring out how to get the mRNA to evade the immune system https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-once-dismissed-idea-became-a-leading-technology-in-the-covid-vaccine-race/ https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-...
- Rebelgecko 6y ago
  Do you (or anyone else on HN) know why mRNA vaccines haven't been used before COVID? Are they more useful against coronavirii? Or is it just that existing vaccines are good enough, so no one has bothered releasing an mRNA vaccine for the mumps or whatever?
dot1x 6y ago
Wow... just wow. You got indoctrinated pretty good hum? You do realize this kind of vaccine never passed animal trials before COVID right? In fact, the company making it never had a successful product before COVID. Yet we're supposed to believe they magically solved the problem in a matter of weeks and all is perfect? Please, submit yourself to be a lab rat, but people like you are the reason why they will force everyone to get the vaccine, freedom be damned.

by Exmoor 6y ago

redisman 6y ago

Pretty incredible and pretty surreal. I honestly wasn't sure how the utterly incompetent federal response of the US would ever dig itself out of this and I guess the answer is here.

akkawwakka 6y ago

It’s worth highlighting that a ton of basic science work went into mRNA vaccine development, starting in the early 1990s: - developing the lipid nanoparticles that the mRNA is delivered in, so your cells could actually take it up intact - figuring out how to get the mRNA to evade the immune system https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-once-dismissed-idea-became-a-leading-technology-in-the-covid-vaccine-race/ https://www.statnews.com/2020/11/10/the-story-of-mrna-how-a-...

Rebelgecko 6y ago
Do you (or anyone else on HN) know why mRNA vaccines haven't been used before COVID? Are they more useful against coronavirii? Or is it just that existing vaccines are good enough, so no one has bothered releasing an mRNA vaccine for the mumps or whatever?

dot1x 6y ago

Wow... just wow. You got indoctrinated pretty good hum? You do realize this kind of vaccine never passed animal trials before COVID right? In fact, the company making it never had a successful product before COVID. Yet we're supposed to believe they magically solved the problem in a matter of weeks and all is perfect? Please, submit yourself to be a lab rat, but people like you are the reason why they will force everyone to get the vaccine, freedom be damned.