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Pharma companies don't feel any embarrassment because it's really not much of a priority for them. Protein structure determination simply isn’t a rate-limiting
by _Wintermute 6y ago
Pharma companies don't feel any embarrassment because it's really not much of a priority for them. Protein structure determination simply isn’t a rate-limiting step in drug discovery in general. [1]
[1] https://blogs.sciencemag.org/pipeline/archives/2019/09/25/whats-crucial-and-what-isnt https://blogs.sciencemag.org/pipeline/archives/2019/09/25/wh...
- dekhn 6y agoThat is true but every pharma has a structural biology department that solves product-related crystal structures with the intent of using that data to speed development. It's an established thing, $100+M/year budget per company. Generally well-respected and considered some of the most important IP the company can generate. They also have theory groups which try to do structure prediction and drug docking but I don't think those groups get any respect inside the companies any more.