3 ms·
Intuitively I don’t understand how annihilating your serotonin supply on a monthly basis can be without negative side effects. The rat studies, while imperfect
by serjester 6y ago
Intuitively I don’t understand how annihilating your serotonin supply on a monthly basis can be without negative side effects.
The rat studies, while imperfect, point to neurotoxicity [1]. The longitudinal studies also show negative long term effects [2]. Even Shulgin, the man that "discovered" MDMA, advises against using more than 4 times a year [3].
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705495/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705495/
[2] https://www.ncbi.nlm.nih.gov/books/NBK56825/ https://www.ncbi.nlm.nih.gov/books/NBK56825/
[3] PIHKAL, Shulgin
- eyelidlessness 6y agoHow many drinks of alcohol are advised against by professionals, and how many do you find alarming in practical reality? What’s the delta? Milligrams of THC? What’s the recommended maximum for any commonly consumed drug versus known safe usage?
- krageon 6y agoYou need to judge MDMA and every other drug next to the reality of alcohol use (which is definitely also terrible for your brain). Not just from a realistic perspective, but purposefully as an acknowledgement that you have been emotionally indoctrinated to judge some things more harshly than others.