4 ms·
He’s done MDMA almost a 100 times, how is he not worried? While I tend to think much of the stigma around drugs is overblown, anyone that knows anything about M
by serjester 6y ago
He’s done MDMA almost a 100 times, how is he not worried? While I tend to think much of the stigma around drugs is overblown, anyone that knows anything about MDMA will tell you this is insanity.
As the saying goes, you can’t manage what you can’t measure so at least he’s got that going for him.
- eyelidlessness 6y agoI know plenty about MDMA and 100 separate usages over many years doesn’t even register on my worry meter.
- serjester 6y agoIntuitively I don’t understand how annihilating your serotonin supply on a monthly basis can be without negative side effects. The rat studies, while imperfect, point to neurotoxicity [1]. The longitudinal studies also show negative long term effects [2]. Even Shulgin, the man that "discovered" MDMA, advises against using more than 4 times a year [3]. [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705495/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705495/ [2] https://www.ncbi.nlm.nih.gov/books/NBK56825/ https://www.ncbi.nlm.nih.gov/books/NBK56825/ [3] PIHKAL, Shulgin
- eyelidlessness 6y agoHow many drinks of alcohol are advised against by professionals, and how many do you find alarming in practical reality? What’s the delta? Milligrams of THC? What’s the recommended maximum for any commonly consumed drug versus known safe usage?
- krageon 6y agoYou need to judge MDMA and every other drug next to the reality of alcohol use (which is definitely also terrible for your brain). Not just from a realistic perspective, but purposefully as an acknowledgement that you have been emotionally indoctrinated to judge some things more harshly than others.