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Curious, are people planning to take the first vaccine that becomes available? I can't imagine taking a vaccine for covid anytime soon, least of all as the firs

Curious, are people planning to take the first vaccine that becomes available? I can't imagine taking a vaccine for covid anytime soon, least of all as the first round.

dgritsko 6y ago
I've generally been of the opinion that by the time it becomes available to me (I'm not in an especially at-risk demographic, not a healthcare worker, etc.), I won't be part of the "first round," and we'll know a good bit more about the safety of these vaccines than we currently do (which is already a decent bit as I understand it, given the size of these trials).
dageshi 6y ago
If my countries healthcare professionals are willing to take it then I will. They're more qualified to judge the risk than anyone else.
- CodeGlitch 6y ago
  Upvoted. This is my general rule in life: do what the professionals do. Of course I have family members who are completely mistrusting of, say, medical professionals, and believe crap on the internet instead.
- Eric_WVGG 6y ago
  Yeah, that's the thing… > I can't imagine taking a vaccine for covid anytime soon, least of all as the first round. Well good for you, unless you're a doctor or nurse, you can’t. And by the time you ^are^ eligible, there will be millions of others who have the vaccine, and more data. Granted, not the months or years of data you usually see with a vaccine, but that’s as abnormal as everything else these days…
- toast0 6y ago
  Healthcare professionals may be more qualified to judge medical risks. But ultimately it's a decision taken with no long term data for either the status quo or the intervention. You can extrapolate long term data from SARS and MERS for tail risks of contracting COVID; but there's no other similar immunizations to extrapolate from. By the time a vaccine is available for me (not in any risk categories; fairly poor access to COVID testing in my county, which I assume would mean poor access to vaccines, too), I'd guess we would have a lot more data on any immediate negative effects, so there's some confidence building; but it's still a choice between an unknowable risk and an unknowable risk.
  - dageshi 6y ago
    There would be immediate quantifiable benefits in terms of how people live their lives however. Being vaccinated is likely to allow society to move back to some level of normalcy. Balanced against long term unknowable personal health risk as you say. In the end my pov is it's better to get on with living now and if a vaccine offers that then I'll take it.
  - deleted 6y ago
    [deleted]
- odessacubbage 6y ago
  they didn't judge the risks of oxycontin very well. as a general rule judgement is largely an evaluation made based on past results... do we have any precedent of a vaccine being fast tracked like this? presumably the safeguards in place exist for a reason, if not then why isn't every vaccine fast tracked?
  - corin_ 6y ago
    You can never guarantee that in the future we won't realise an existing consensus won't be shown to be flawed, but without the benefit of hindsight is there any option more consistently reliable than following healthcare professionals & experts in related scientific fields?
  - fsagx 6y ago
    Yes, In the US in 1976. https://www.history.com/news/swine-flu-rush-vaccine-election-year-1976 https://www.history.com/news/swine-flu-rush-vaccine-election... https://en.wikipedia.org/wiki/1976_swine_flu_outbreak https://en.wikipedia.org/wiki/1976_swine_flu_outbreak
lawn 6y ago
While I'd rather see people with higher risk than me get the vaccine first, I would absolutely take it if I was able to.
- donor20 6y ago
  I'd rather school teachers got them so I could stay home and work.
brlewis 6y ago
Help me understand what risk you're concerned about. Have there been other mRNA vaccines where an adverse effect showed up in general use that wasn't caught in clinical trials?
- ars 6y ago
  There haven't been any other mRNA vaccines at all. This is the very first one, and on an accelerated schedule. So the answer to your question is unknown, and whoever goes first gets to be part of the large study answering that question. Personally I'm going to wait for either a conventional vaccine, or at least a year or so by lots of other people. (It helps that I'm 90% sure I had it already, and I'm low risk on top of that.)
  - nojito 6y ago
    There’s nothing accelerated about it. Plus severe side effects would have been seen during phase 3 trials anyway.
- zaroth 6y ago
  > Have there been other mRNA vaccines... There haven’t been other approved mRNA vaccines, period. And COVID just isn’t that big of a concern for most people. There’s every reason for people to decide they don’t want to rush out to get this highly innovative and novel vaccine injected into their bodies.
  - brlewis 6y ago
    Thanks. I only hovered over mRNA on a wikipedia page[0] and saw the word "fragment", so I knew it wasn't live or attenuated viruses, but didn't realize how novel this vaccine type is. That said, I'd still rush out and get it. I'm more concerned about the unknowns of Long Covid than I am about the unknowns of the vaccine. https://en.wikipedia.org/wiki/Long_Covid https://en.wikipedia.org/wiki/Long_Covid [0] https://en.wikipedia.org/wiki/COVID-19_vaccine#Clinical_trials_started_in_2020 https://en.wikipedia.org/wiki/COVID-19_vaccine#Clinical_tria...
deleted 6y ago
[deleted]
WillPostForFood 6y ago
You have to weigh the risk of the vaccine vs the risk of the disease. If you are in 100% control of your exposure, sure wait. But if you aren't in control of your exposure (e.g., have to go to work, have kids in school), then there is no reason to think the risk of the vaccine is anywhere close to the risk of getting Covid. I have kids in school, and can't wait until it is available.
- CodeGlitch 6y ago
  Unless you live in a cave I'm not sure you'll be able to reduce your exposure that much. I mean you go to the shops to buy food right? Supermarkets are the largest vector btw
  - bsder 6y ago
    > Supermarkets are the largest vector btw Cite, please. This matches nothing I have seen. The biggest vectors seem to be Number 1: churches and Number 2: bars/restaurants.
    - errantmind 6y ago
      Cite, please
    - CodeGlitch 6y ago
      Sure: https://news.sky.com/story/covid-19-supermarkets-most-common-exposure-setting-for-catching-coronavirus-in-england-latest-data-shows-12136418 https://news.sky.com/story/covid-19-supermarkets-most-common... Edit: ok re-reading the article it says supermarkets were the most common place visited before testing positive, but then PHE states this is no proof that is where it's contacted.
      - bsder 6y ago
        In fact, it's almost guaranteed to not be the place where you contracted it. I suspect that the issue is that people are going "Oh, I need a Covid test. If it's positive, I'm going to have to semi-quarantine. Let's stop at the grocery store before getting the test."
4rt 6y ago
these flu related vaccines already go to high risk (e.g. elderly) first so a lot of the risk is already factored in to the benefit they can provide. having said that, yes i'd have it if i could go eat in a restaurant again.
deleted 6y ago
[deleted]
dbbk 6y ago
You wouldn't get a choice of vaccine, the NHS would decide.

Curious, are people planning to take the first vaccine that becomes available? I can't imagine taking a vaccine for covid anytime soon, least of all as the first round.

dgritsko 6y ago

I've generally been of the opinion that by the time it becomes available to me (I'm not in an especially at-risk demographic, not a healthcare worker, etc.), I won't be part of the "first round," and we'll know a good bit more about the safety of these vaccines than we currently do (which is already a decent bit as I understand it, given the size of these trials).

dageshi 6y ago

If my countries healthcare professionals are willing to take it then I will. They're more qualified to judge the risk than anyone else.

CodeGlitch 6y ago
Upvoted. This is my general rule in life: do what the professionals do. Of course I have family members who are completely mistrusting of, say, medical professionals, and believe crap on the internet instead.
Eric_WVGG 6y ago
Yeah, that's the thing… > I can't imagine taking a vaccine for covid anytime soon, least of all as the first round. Well good for you, unless you're a doctor or nurse, you can’t. And by the time you ^are^ eligible, there will be millions of others who have the vaccine, and more data. Granted, not the months or years of data you usually see with a vaccine, but that’s as abnormal as everything else these days…
toast0 6y ago
Healthcare professionals may be more qualified to judge medical risks. But ultimately it's a decision taken with no long term data for either the status quo or the intervention. You can extrapolate long term data from SARS and MERS for tail risks of contracting COVID; but there's no other similar immunizations to extrapolate from. By the time a vaccine is available for me (not in any risk categories; fairly poor access to COVID testing in my county, which I assume would mean poor access to vaccines, too), I'd guess we would have a lot more data on any immediate negative effects, so there's some confidence building; but it's still a choice between an unknowable risk and an unknowable risk.
- dageshi 6y ago
  There would be immediate quantifiable benefits in terms of how people live their lives however. Being vaccinated is likely to allow society to move back to some level of normalcy. Balanced against long term unknowable personal health risk as you say. In the end my pov is it's better to get on with living now and if a vaccine offers that then I'll take it.
- deleted 6y ago
  [deleted]
odessacubbage 6y ago
they didn't judge the risks of oxycontin very well. as a general rule judgement is largely an evaluation made based on past results... do we have any precedent of a vaccine being fast tracked like this? presumably the safeguards in place exist for a reason, if not then why isn't every vaccine fast tracked?
- corin_ 6y ago
  You can never guarantee that in the future we won't realise an existing consensus won't be shown to be flawed, but without the benefit of hindsight is there any option more consistently reliable than following healthcare professionals & experts in related scientific fields?
- fsagx 6y ago
  Yes, In the US in 1976. https://www.history.com/news/swine-flu-rush-vaccine-election-year-1976 https://www.history.com/news/swine-flu-rush-vaccine-election... https://en.wikipedia.org/wiki/1976_swine_flu_outbreak https://en.wikipedia.org/wiki/1976_swine_flu_outbreak

lawn 6y ago

While I'd rather see people with higher risk than me get the vaccine first, I would absolutely take it if I was able to.

donor20 6y ago
I'd rather school teachers got them so I could stay home and work.

brlewis 6y ago

Help me understand what risk you're concerned about. Have there been other mRNA vaccines where an adverse effect showed up in general use that wasn't caught in clinical trials?

ars 6y ago
There haven't been any other mRNA vaccines at all. This is the very first one, and on an accelerated schedule. So the answer to your question is unknown, and whoever goes first gets to be part of the large study answering that question. Personally I'm going to wait for either a conventional vaccine, or at least a year or so by lots of other people. (It helps that I'm 90% sure I had it already, and I'm low risk on top of that.)
- nojito 6y ago
  There’s nothing accelerated about it. Plus severe side effects would have been seen during phase 3 trials anyway.
zaroth 6y ago
> Have there been other mRNA vaccines... There haven’t been other approved mRNA vaccines, period. And COVID just isn’t that big of a concern for most people. There’s every reason for people to decide they don’t want to rush out to get this highly innovative and novel vaccine injected into their bodies.
- brlewis 6y ago
  Thanks. I only hovered over mRNA on a wikipedia page[0] and saw the word "fragment", so I knew it wasn't live or attenuated viruses, but didn't realize how novel this vaccine type is. That said, I'd still rush out and get it. I'm more concerned about the unknowns of Long Covid than I am about the unknowns of the vaccine. https://en.wikipedia.org/wiki/Long_Covid https://en.wikipedia.org/wiki/Long_Covid [0] https://en.wikipedia.org/wiki/COVID-19_vaccine#Clinical_trials_started_in_2020 https://en.wikipedia.org/wiki/COVID-19_vaccine#Clinical_tria...

deleted 6y ago

[deleted]

WillPostForFood 6y ago

You have to weigh the risk of the vaccine vs the risk of the disease. If you are in 100% control of your exposure, sure wait. But if you aren't in control of your exposure (e.g., have to go to work, have kids in school), then there is no reason to think the risk of the vaccine is anywhere close to the risk of getting Covid. I have kids in school, and can't wait until it is available.

CodeGlitch 6y ago
Unless you live in a cave I'm not sure you'll be able to reduce your exposure that much. I mean you go to the shops to buy food right? Supermarkets are the largest vector btw
- bsder 6y ago
  > Supermarkets are the largest vector btw Cite, please. This matches nothing I have seen. The biggest vectors seem to be Number 1: churches and Number 2: bars/restaurants.
  - errantmind 6y ago
    Cite, please
  - CodeGlitch 6y ago
    Sure: https://news.sky.com/story/covid-19-supermarkets-most-common-exposure-setting-for-catching-coronavirus-in-england-latest-data-shows-12136418 https://news.sky.com/story/covid-19-supermarkets-most-common... Edit: ok re-reading the article it says supermarkets were the most common place visited before testing positive, but then PHE states this is no proof that is where it's contacted.
    - bsder 6y ago
      In fact, it's almost guaranteed to not be the place where you contracted it. I suspect that the issue is that people are going "Oh, I need a Covid test. If it's positive, I'm going to have to semi-quarantine. Let's stop at the grocery store before getting the test."

4rt 6y ago

these flu related vaccines already go to high risk (e.g. elderly) first so a lot of the risk is already factored in to the benefit they can provide. having said that, yes i'd have it if i could go eat in a restaurant again.

deleted 6y ago

[deleted]

dbbk 6y ago

You wouldn't get a choice of vaccine, the NHS would decide.