4 ms·

Short term, high-dose Vitamin D supplementation for Covid, a randomised trial

33 points by belltaco 6y ago

nwah1 6y ago
60,000 IU is a ton, but very interesting. A clinical study on very high dose Vitamin C in China needed to be halted because the virus was under control there and they were unable to recruit any infected study participants. Would be very interested to see the same study attempted here. https://clinicaltrials.gov/ct2/show/NCT04264533 https://clinicaltrials.gov/ct2/show/NCT04264533 Also have seen reasons to be hopeful about high dose melatonin, zinc, allicin, curcumin, magnesium, and NAC.
- mhkool 6y ago
  prof dr Cicero Coimbra uses 600,000 IU in a single dose to get 70 ng/ml after 3days and got very good results (do not recall details).
- treeman79 6y ago
  I have a prescription for a 50,000 once a week. I was highly skeptical about it. But nerve pain and migraines have reduced noticeably on it.
efficax 6y ago
It's fascinating how obsessed this site is with vitamin d. I mean I take it myself but really y'all are fixated on it
- throwawaybutwhy 6y ago
  It's not the site, it's the zealots. Rustafarians, anti-Muskers, note-takers, NY Times 'submarine fans' and supplementary *calciferol proponents have more or less hacked Hacker News post visibility algorithms.
  - dunce2020 6y ago
    The fruit-juice drinkers, nudists, sandal-wearers, sex-maniacs, Quakers, ‘Nature Cure’ quacks, pacifists and feminists are all behind Big Vitamin D.
  - hyperman1 6y ago
    I have to admit I rather like the sound of 'rustafarians'. Yo màn. Be safe. Take care of your lifetime, maaan. I would join the movement, except I suspect I already have.
    - throwawaybutwhy 6y ago
      Alas, not my invention: [0]. Oh, and thanks, will check my borrowings. [0] https://news.ycombinator.com/item?id=9552341 https://news.ycombinator.com/item?id=9552341
    - jrootabega 6y ago
      We've gotten a lot of mileage out of that. Trustafarian, Pastafarian, Matzofarian...
gpapilion 6y ago
Interesting that the intervention seems that effective. The difference between the groups is stunning.
tetromino_ 6y ago
Important note for those only skimming the article: all participants in this study were vitamin D deficient (25(OH)D<20 ng/ml) individuals.
antman 6y ago
Anyone knows if that is common?: "Data availability statement - Data are available upon reasonable request."
nradov 6y ago
The same treatment has reportedly been used successfully to treat influenza since at least 2015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463890/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463890/
LionBlack8 6y ago
I'm a Vit D3 taker, not because of Covid, but because my levels years ago were very low, and they need to be maintained in the reference range, which is easy to do with supplementation by https://www.vitasave.ca/ https://www.vitasave.ca/ . I need to stay out of the sun as I'm very fair, burn quickly, and don't want any (more) skin damage or freckles or age spots, so using sunshine to build levels isn't the right solution.
ronronron09 6y ago
I am a Vit D3 taker, not because of Covid, but because my levels years ago were very low, and they need to be maintained in the reference range, which is easy to do with supplementation by https://www.vitasave.ca/ https://www.vitasave.ca/ . I need to stay out of the sun as I'm very fair, burn quickly, and don't want any (more) skin damage or freckles or age spots, so using sunshine to build levels isn't the right solution.

33 points by belltaco 6y ago

60,000 IU is a ton, but very interesting. A clinical study on very high dose Vitamin C in China needed to be halted because the virus was under control there and they were unable to recruit any infected study participants. Would be very interested to see the same study attempted here. https://clinicaltrials.gov/ct2/show/NCT04264533 https://clinicaltrials.gov/ct2/show/NCT04264533 Also have seen reasons to be hopeful about high dose melatonin, zinc, allicin, curcumin, magnesium, and NAC.

mhkool 6y ago
prof dr Cicero Coimbra uses 600,000 IU in a single dose to get 70 ng/ml after 3days and got very good results (do not recall details).
treeman79 6y ago
I have a prescription for a 50,000 once a week. I was highly skeptical about it. But nerve pain and migraines have reduced noticeably on it.

efficax 6y ago

It's fascinating how obsessed this site is with vitamin d. I mean I take it myself but really y'all are fixated on it

throwawaybutwhy 6y ago
It's not the site, it's the zealots. Rustafarians, anti-Muskers, note-takers, NY Times 'submarine fans' and supplementary *calciferol proponents have more or less hacked Hacker News post visibility algorithms.
- dunce2020 6y ago
  The fruit-juice drinkers, nudists, sandal-wearers, sex-maniacs, Quakers, ‘Nature Cure’ quacks, pacifists and feminists are all behind Big Vitamin D.
- hyperman1 6y ago
  I have to admit I rather like the sound of 'rustafarians'. Yo màn. Be safe. Take care of your lifetime, maaan. I would join the movement, except I suspect I already have.
  - throwawaybutwhy 6y ago
    Alas, not my invention: [0]. Oh, and thanks, will check my borrowings. [0] https://news.ycombinator.com/item?id=9552341 https://news.ycombinator.com/item?id=9552341
  - jrootabega 6y ago
    We've gotten a lot of mileage out of that. Trustafarian, Pastafarian, Matzofarian...

gpapilion 6y ago

Interesting that the intervention seems that effective. The difference between the groups is stunning.

tetromino_ 6y ago

Important note for those only skimming the article: all participants in this study were vitamin D deficient (25(OH)D<20 ng/ml) individuals.

antman 6y ago

Anyone knows if that is common?: "Data availability statement - Data are available upon reasonable request."

nradov 6y ago

The same treatment has reportedly been used successfully to treat influenza since at least 2015. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463890/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463890/

LionBlack8 6y ago

I'm a Vit D3 taker, not because of Covid, but because my levels years ago were very low, and they need to be maintained in the reference range, which is easy to do with supplementation by https://www.vitasave.ca/ https://www.vitasave.ca/ . I need to stay out of the sun as I'm very fair, burn quickly, and don't want any (more) skin damage or freckles or age spots, so using sunshine to build levels isn't the right solution.

ronronron09 6y ago

I am a Vit D3 taker, not because of Covid, but because my levels years ago were very low, and they need to be maintained in the reference range, which is easy to do with supplementation by https://www.vitasave.ca/ https://www.vitasave.ca/ . I need to stay out of the sun as I'm very fair, burn quickly, and don't want any (more) skin damage or freckles or age spots, so using sunshine to build levels isn't the right solution.