7 ms·

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU p

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

eloff 6y ago
There's an expert that specializes in vitamin D toxicity cases and regularly posts here. She sees cases at less than the 10000IU daily dose Fauci takes. I would be hesitant to go above 4000IU daily without monitoring blood levels every six months or so. Its winter here in Canada, I'm taking 3000IU per day. I drop that to 1000IU in the summer. I'm not a doctor, not recommending you do the same. Just sharing.
- nerbert 6y ago
  Obvious warning but there's a lot of name dropping and I'm not sure what leads people to think Fauci 1) takes 10kUI or 6kUI per day 2) that it's the right dose for them 3) that they can make conclusions on what to do with their health based on a forum. Get your blood checked, get recommendation from a doctor... before supercharging your blood with calcium & other fun stuff...
  - monetus 6y ago
    The 10,000 number is hearsay I overheard as a family member listened to this english nurse who professed to taking 5,000 himself. - https://youtube.com/user/Campbellteaching https://youtube.com/user/Campbellteaching I imagine someone reading this may not have healthcare coverage, but bloodwork can be cheap! Save up! Please be cautious
- ardy42 6y ago
  > I would be hesitant to go above 4000IU daily without monitoring blood levels every six months or so. I did that for a little while (though the nurse practitioner at my work clinic wasn't too keen on signing off on non-medically indicated blood tests). IIRC, I was supplementing at 5000IU a day and after a few months wound up with a higher blood level than I was comfortable with, based on the ranges that came with the tests. After that, I reduced down to 2000IU a day or less. I've been much less into supplements in general, but I only take 2000IU irregularly now.
- jmnicolas 6y ago
  Just sharing too: I was taking 3000IU per day like you and noticed really positive changes to my mood and general wellness by increasing to 9k (my pills are 3k each). But since seeing the alarming articles on HN I reduced a bit, and I'm thinking of getting my blood tested.
- mattmanser 6y ago
  Her post about someone with serious health problems with over-dosing vit d (in this case, just 5,000 UI): https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-story https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-st... Her post about vit d in general: https://www.devaboone.com/post/vitamin-d-part-1-back-to-basics https://www.devaboone.com/post/vitamin-d-part-1-back-to-basi...
  - raverbashing 6y ago
    > 5000 international units (IUs) daily. Five years later Five years. Of 5000 IUs per day Five years. Of more than 10x the EU RDA (and maybe 5x more than the US RDA, still) But please tell me again how easy it is to overdose
    - mattmanser 6y ago
      I admit I didn't make that clear, the point was 5k UI is not healthy to take long term. But you build a supplement regime around it, and then just keep taking it for years. That's how easy it is. And in another thread a guy was saying his daily D3 was 20,000 IU a day as if it was perfectly normal. I was found to be extremely deficient in a blood test and personally been prescribed 10k UI, or maybe even 50k I can't remember, but it was a weekly tablet for only 6 weeks.
- wavegeek 6y ago
  Yes I read that report and was not convinced. One anecdote. Not in a peer reviewed journal etc. If you do take Vitamin D, variant D3 is by far best, and it may be wise to take vitamin K2 as well to avoid calcium metabolism issues (calcification).
- neuronic 6y ago
  The problem is TIME. Taking 10,000 IU for a medium amount of time will very very likely be fine. But due to fat solubility and therefore slow build up in the body, you are increasingly growing towards toxic levels over a long time. The body can only regulate vitamin D before synthesis, after sunlight exposure. But if you take already-synthesized vitamin D, that regulation won't kick in and you're free to get hypervitaminosis. Time in combination with individual biology are what brings issues here. Get blood work done (it cost me 30€ in Germany but was combined with 2 other tests).
  - im3w1l 6y ago
    On the one hand yes you could take it for a short time, but on the other why take excessive doses at all and risk falling into a bad habit? When there are lower doses that are both effective and safe?
29athrowaway 6y ago
From "The Big Vitamin D Mistake" by Dimitrios T. Papadimitriou (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/) > This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter. Actions are urgently needed to protect the global population from vitamin D deficiency. Then, a person that consumed from 8000 IU to 12000 IU per day and had kidney damage due to high calcium levels in his blood. https://www.webmd.com/vitamins-and-supplements/news/20190408/for-one-man-too-much-vitamin-d-was-disastrous https://www.webmd.com/vitamins-and-supplements/news/20190408...
- buggythebug 6y ago
  Author is Greek. Don't trust him.
- code51 6y ago
  What about D3K2 supplementation (adding in K2 supplementation) to counter these high levels of calcium?
roel_v 6y ago
I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how easy is it to get preventative tests done where you live, and what does it cost?
- Fnoord 6y ago
  "A real medical indication." This is anecdotal, but I just told my doctor (GP) my symptoms, that I am vegan and hence don't eat milk products. I was also on quitting smoking. Got a reference for blood test and smoking cessation (Zyban). I don't remember if smoking cessation was insured, but the rest all was. Going to your GP is free (via mandatory insurance) in The Netherlands. I got my vitamin D and B12 checked among other things.
- lultimouomo 6y ago
  If you are taking vitamin D supplementation, your physician will surely prescribe you periodic testing, at the very least if you ask for it. But since I have a private testing point just beside my office, I go there without doctor prescription; last time it cost me 17€ to get my vitamin D checked. This is in Italy.
  - blub 6y ago
    In Germany you have to pay (35-40 EUR) for your blood test to check for deficiency even if you were previously found deficient and must re-check after supplementing. My doctor also doesn't give a fuck and never asked me to re-test.
- ps2fats 6y ago
  I understand why this is the way it is (cost-savings), but this needs to change. It has been shown that preventative screening can be very cost effective as opposed to reactive treatment.
- 6y ago
tgsovlerkhgsel 6y ago
Source for the Fauci claim? I've seen a claim of 6000 (not sourced properly), the RDA is 600, I couldn't find even a dubious source for 10000 and all decent sources didn't give a dose at all. Given that 10000 is considered more than the maximum safe amount by many health authorities, I doubt Fauci would say he's taking that much even if he did.
- sharedfrog 6y ago
  The Big Vitamin D Mistake: https://pubmed.ncbi.nlm.nih.gov/28768407/ https://pubmed.ncbi.nlm.nih.gov/28768407/ > A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values ≥50 nmol/L. > This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter.
collyw 6y ago
What is IU compared to micrograms? (Is it international units? My girlfriend mentioned this measure to me this morning when I gave her a vitamin tabled measured in micrograms, I don't know much about it).
- swebs 6y ago
  It depends on the vitamin. 1 microgram of vitamin D is 40 IU.
draugadrotten 6y ago
> Fauci said he takes 10,000IU per day. Source please? I find Fauci said 6,000IU https://vitamindwiki.com/Dr.+Fauci+takes+6%2C000+IU+of+Vitamin+D+daily+%E2%80%93+Sept+2020 https://vitamindwiki.com/Dr.+Fauci+takes+6%2C000+IU+of+Vitam...

For reference: The level of toxicity listed in your link is 60,000IU per day. Fauci said he takes 10,000IU per day. The bottle I purchased recommends 2,000IU per day. Get your blood work done people.

eloff 6y ago

There's an expert that specializes in vitamin D toxicity cases and regularly posts here. She sees cases at less than the 10000IU daily dose Fauci takes. I would be hesitant to go above 4000IU daily without monitoring blood levels every six months or so. Its winter here in Canada, I'm taking 3000IU per day. I drop that to 1000IU in the summer. I'm not a doctor, not recommending you do the same. Just sharing.

nerbert 6y ago
Obvious warning but there's a lot of name dropping and I'm not sure what leads people to think Fauci 1) takes 10kUI or 6kUI per day 2) that it's the right dose for them 3) that they can make conclusions on what to do with their health based on a forum. Get your blood checked, get recommendation from a doctor... before supercharging your blood with calcium & other fun stuff...
- monetus 6y ago
  The 10,000 number is hearsay I overheard as a family member listened to this english nurse who professed to taking 5,000 himself. - https://youtube.com/user/Campbellteaching https://youtube.com/user/Campbellteaching I imagine someone reading this may not have healthcare coverage, but bloodwork can be cheap! Save up! Please be cautious
ardy42 6y ago
> I would be hesitant to go above 4000IU daily without monitoring blood levels every six months or so. I did that for a little while (though the nurse practitioner at my work clinic wasn't too keen on signing off on non-medically indicated blood tests). IIRC, I was supplementing at 5000IU a day and after a few months wound up with a higher blood level than I was comfortable with, based on the ranges that came with the tests. After that, I reduced down to 2000IU a day or less. I've been much less into supplements in general, but I only take 2000IU irregularly now.
jmnicolas 6y ago
Just sharing too: I was taking 3000IU per day like you and noticed really positive changes to my mood and general wellness by increasing to 9k (my pills are 3k each). But since seeing the alarming articles on HN I reduced a bit, and I'm thinking of getting my blood tested.
mattmanser 6y ago
Her post about someone with serious health problems with over-dosing vit d (in this case, just 5,000 UI): https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-story https://www.devaboone.com/post/vitamin-d-part-2-shannon-s-st... Her post about vit d in general: https://www.devaboone.com/post/vitamin-d-part-1-back-to-basics https://www.devaboone.com/post/vitamin-d-part-1-back-to-basi...
- raverbashing 6y ago
  > 5000 international units (IUs) daily. Five years later Five years. Of 5000 IUs per day Five years. Of more than 10x the EU RDA (and maybe 5x more than the US RDA, still) But please tell me again how easy it is to overdose
  - mattmanser 6y ago
    I admit I didn't make that clear, the point was 5k UI is not healthy to take long term. But you build a supplement regime around it, and then just keep taking it for years. That's how easy it is. And in another thread a guy was saying his daily D3 was 20,000 IU a day as if it was perfectly normal. I was found to be extremely deficient in a blood test and personally been prescribed 10k UI, or maybe even 50k I can't remember, but it was a weekly tablet for only 6 weeks.
wavegeek 6y ago
Yes I read that report and was not convinced. One anecdote. Not in a peer reviewed journal etc. If you do take Vitamin D, variant D3 is by far best, and it may be wise to take vitamin K2 as well to avoid calcium metabolism issues (calcification).
neuronic 6y ago
The problem is TIME. Taking 10,000 IU for a medium amount of time will very very likely be fine. But due to fat solubility and therefore slow build up in the body, you are increasingly growing towards toxic levels over a long time. The body can only regulate vitamin D before synthesis, after sunlight exposure. But if you take already-synthesized vitamin D, that regulation won't kick in and you're free to get hypervitaminosis. Time in combination with individual biology are what brings issues here. Get blood work done (it cost me 30€ in Germany but was combined with 2 other tests).
- im3w1l 6y ago
  On the one hand yes you could take it for a short time, but on the other why take excessive doses at all and risk falling into a bad habit? When there are lower doses that are both effective and safe?

29athrowaway 6y ago

From "The Big Vitamin D Mistake" by Dimitrios T. Papadimitriou (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541280/) > This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter. Actions are urgently needed to protect the global population from vitamin D deficiency. Then, a person that consumed from 8000 IU to 12000 IU per day and had kidney damage due to high calcium levels in his blood. https://www.webmd.com/vitamins-and-supplements/news/20190408/for-one-man-too-much-vitamin-d-was-disastrous https://www.webmd.com/vitamins-and-supplements/news/20190408...

buggythebug 6y ago
Author is Greek. Don't trust him.
code51 6y ago
What about D3K2 supplementation (adding in K2 supplementation) to counter these high levels of calcium?

roel_v 6y ago

I always see Americans (apologies for making assumptions if you're not) throw around blood testing like it's something trivial and casually done. Here in the Netherlands, it takes a real medical indication and some pushing of a doctor to get any testing done. Alternatively, you use a private testing company that costs 200 to 400 euros for a comprehensive screening. Question to the public in various countries - how easy is it to get preventative tests done where you live, and what does it cost?

Fnoord 6y ago
"A real medical indication." This is anecdotal, but I just told my doctor (GP) my symptoms, that I am vegan and hence don't eat milk products. I was also on quitting smoking. Got a reference for blood test and smoking cessation (Zyban). I don't remember if smoking cessation was insured, but the rest all was. Going to your GP is free (via mandatory insurance) in The Netherlands. I got my vitamin D and B12 checked among other things.
lultimouomo 6y ago
If you are taking vitamin D supplementation, your physician will surely prescribe you periodic testing, at the very least if you ask for it. But since I have a private testing point just beside my office, I go there without doctor prescription; last time it cost me 17€ to get my vitamin D checked. This is in Italy.
- blub 6y ago
  In Germany you have to pay (35-40 EUR) for your blood test to check for deficiency even if you were previously found deficient and must re-check after supplementing. My doctor also doesn't give a fuck and never asked me to re-test.
ps2fats 6y ago
I understand why this is the way it is (cost-savings), but this needs to change. It has been shown that preventative screening can be very cost effective as opposed to reactive treatment.
6y ago

tgsovlerkhgsel 6y ago

Source for the Fauci claim? I've seen a claim of 6000 (not sourced properly), the RDA is 600, I couldn't find even a dubious source for 10000 and all decent sources didn't give a dose at all. Given that 10000 is considered more than the maximum safe amount by many health authorities, I doubt Fauci would say he's taking that much even if he did.

sharedfrog 6y ago
The Big Vitamin D Mistake: https://pubmed.ncbi.nlm.nih.gov/28768407/ https://pubmed.ncbi.nlm.nih.gov/28768407/ > A statistical error in the estimation of the recommended dietary allowance (RDA) for vitamin D was recently discovered; in a correct analysis of the data used by the Institute of Medicine, it was found that 8895 IU/d was needed for 97.5% of individuals to achieve values ≥50 nmol/L. > This could lead to a recommendation of 1000 IU for children <1 year on enriched formula and 1500 IU for breastfed children older than 6 months, 3000 IU for children >1 year of age, and around 8000 IU for young adults and thereafter.

collyw 6y ago

What is IU compared to micrograms? (Is it international units? My girlfriend mentioned this measure to me this morning when I gave her a vitamin tabled measured in micrograms, I don't know much about it).

swebs 6y ago
It depends on the vitamin. 1 microgram of vitamin D is 40 IU.

draugadrotten 6y ago

> Fauci said he takes 10,000IU per day. Source please? I find Fauci said 6,000IU https://vitamindwiki.com/Dr.+Fauci+takes+6%2C000+IU+of+Vitamin+D+daily+%E2%80%93+Sept+2020 https://vitamindwiki.com/Dr.+Fauci+takes+6%2C000+IU+of+Vitam...