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> I've been microdosing psilocybin daily for the past six months [...] I didn't get COVID and I feel a lot more switched on and focused You lost your causation

> I've been microdosing psilocybin daily for the past six months [...] I didn't get COVID and I feel a lot more switched on and focused You lost your causation vs correlation sense though :)

agumonkey 6y ago
he's now fully quantum
qz2 6y ago
Nailed it. A lot of the "I did this and it had great effects" are compounded with "I did this and it ruined my life" and a bit of "I did this and it ruined my life and everyone around me". I suspect the human mind is tailored to promote the first outcome and stick it's fingers in its metaphorical ears about the last two outcomes. Turns out we need actual formal studies and even those aren't necessarily conclusive so it's best to err on the side of caution.
- mimac 6y ago
  Good evidence that big doses work: https://journals.sagepub.com/doi/abs/10.1177/0269881120919957 https://journals.sagepub.com/doi/abs/10.1177/026988112091995...
  - qz2 6y ago
    I’m sure that is caveated on some people and for some conditions. I’d expect a better standard and more research to be defined here or we’ll end up with another paroxetine mess on our hands. I lost a decade of my life to cleaning up after that mess and that was just a family member’s encounter with it. What is factual is that things are invariably more complicated than they look when it comes to human minds. Look up “study 329” for an example of complexity.
- dmurray 6y ago
  > I suspect the human mind is tailored to promote the first outcome and stick it's fingers in its metaphorical ears about the last two outcomes. It's more complicated than that. Plenty of people hear the bad outcomes and stick their fingers in their ears about the good ones. The subject of recreational drug use is a particularly good one for eliciting this behaviour, both for and against. The interesting questions are how people in the same society get primed for one reaction over the other, and how we can individually avoid this behaviour and approach controversial topics with an open mind.
  - adamsea 6y ago
    And (although I think you kinda said this), different people may respond in different ways.
PakG1 6y ago
This sounds too much like Billions season 5 episode 7. Uncanny. https://www.youtube.com/watch?v=XtJNljm1pVs https://www.youtube.com/watch?v=XtJNljm1pVs
- okamiueru 6y ago
  Is that clip indicative of the quality of the show?
  - drewmate 6y ago
    Currently, yes. The first season was _much_ better, and there has been a decline (at first steep, then gradual and consistent) with each season since then. This was the last episode they aired due to COVID-related production shutdown. They're supposed to finish this season and do another, but I wonder if the show might just shut down quietly at this point.
    - toby 6y ago
      It was initially based on a true story described in the book "Black Edge". It just kept getting more and more outlandish once they ran out of source material.
f69281c 6y ago
The self-reported positive effects hallucinogens are awful. They alter your perception so your perception of perceived benefits is unreliable, and anyone who's not tripping can tell you that. I mean, with full doses the reported benefits are things like connecting with the thread of the universe and speaking across planes to dimensional beings that inform you that we're all one, but the word fractal is jammed in there somewhere. I'm not saying these people can't have fun, but pulling THAT experience back to just reduced levels of the drug is probably still going to give terrible accuracy for self reported results. Microdosing reminds me of those people who left high school parties saying it was fine because they drive better drunk, or that they took some coke to balance it out.
- teataster 6y ago
  Microdosing implies non psychoactive dose. It would be more like people who left after drinking one beer because they were not under the influence. Furthermore, how can you be certain that you sober perception is more accurate than the altered one? How can you be certain that the effects of microdosing are even comparable to full doses? I am not making claims either way, just asking.
- loves_mangoes 6y ago
  Here's my personal anecdote: I took acid once (200ug sublingual), and realized that I need to clean my apartment and brush my teeth more often. I'm not a very spiritual person, and I don't have a strong desire to 'connect with the thread of the universe'. But I'm very curious and happy to try things, if I can convince myself they're reasonably safe. That was a few weeks ago, and I'm happy to report that my floor is noticeably cleaner and my teeth cared for =) I could try to claim other less measurable and subjective benefits, but that wouldn't be very honest with myself after only a couple weeks, and I doubt you'd believe me.
- travisjungroth 6y ago
  If someone is impaired to drive they are by definition not microdosing. The equivalent to alcohol would be like a quarter of a beer.

> I've been microdosing psilocybin daily for the past six months [...] I didn't get COVID and I feel a lot more switched on and focused You lost your causation vs correlation sense though :)

agumonkey 6y ago

he's now fully quantum

qz2 6y ago

Nailed it. A lot of the "I did this and it had great effects" are compounded with "I did this and it ruined my life" and a bit of "I did this and it ruined my life and everyone around me". I suspect the human mind is tailored to promote the first outcome and stick it's fingers in its metaphorical ears about the last two outcomes. Turns out we need actual formal studies and even those aren't necessarily conclusive so it's best to err on the side of caution.

mimac 6y ago
Good evidence that big doses work: https://journals.sagepub.com/doi/abs/10.1177/0269881120919957 https://journals.sagepub.com/doi/abs/10.1177/026988112091995...
- qz2 6y ago
  I’m sure that is caveated on some people and for some conditions. I’d expect a better standard and more research to be defined here or we’ll end up with another paroxetine mess on our hands. I lost a decade of my life to cleaning up after that mess and that was just a family member’s encounter with it. What is factual is that things are invariably more complicated than they look when it comes to human minds. Look up “study 329” for an example of complexity.
dmurray 6y ago
> I suspect the human mind is tailored to promote the first outcome and stick it's fingers in its metaphorical ears about the last two outcomes. It's more complicated than that. Plenty of people hear the bad outcomes and stick their fingers in their ears about the good ones. The subject of recreational drug use is a particularly good one for eliciting this behaviour, both for and against. The interesting questions are how people in the same society get primed for one reaction over the other, and how we can individually avoid this behaviour and approach controversial topics with an open mind.
- adamsea 6y ago
  And (although I think you kinda said this), different people may respond in different ways.

PakG1 6y ago

This sounds too much like Billions season 5 episode 7. Uncanny. https://www.youtube.com/watch?v=XtJNljm1pVs https://www.youtube.com/watch?v=XtJNljm1pVs

okamiueru 6y ago
Is that clip indicative of the quality of the show?
- drewmate 6y ago
  Currently, yes. The first season was _much_ better, and there has been a decline (at first steep, then gradual and consistent) with each season since then. This was the last episode they aired due to COVID-related production shutdown. They're supposed to finish this season and do another, but I wonder if the show might just shut down quietly at this point.
  - toby 6y ago
    It was initially based on a true story described in the book "Black Edge". It just kept getting more and more outlandish once they ran out of source material.

f69281c 6y ago

The self-reported positive effects hallucinogens are awful. They alter your perception so your perception of perceived benefits is unreliable, and anyone who's not tripping can tell you that. I mean, with full doses the reported benefits are things like connecting with the thread of the universe and speaking across planes to dimensional beings that inform you that we're all one, but the word fractal is jammed in there somewhere. I'm not saying these people can't have fun, but pulling THAT experience back to just reduced levels of the drug is probably still going to give terrible accuracy for self reported results. Microdosing reminds me of those people who left high school parties saying it was fine because they drive better drunk, or that they took some coke to balance it out.

teataster 6y ago
Microdosing implies non psychoactive dose. It would be more like people who left after drinking one beer because they were not under the influence. Furthermore, how can you be certain that you sober perception is more accurate than the altered one? How can you be certain that the effects of microdosing are even comparable to full doses? I am not making claims either way, just asking.
loves_mangoes 6y ago
Here's my personal anecdote: I took acid once (200ug sublingual), and realized that I need to clean my apartment and brush my teeth more often. I'm not a very spiritual person, and I don't have a strong desire to 'connect with the thread of the universe'. But I'm very curious and happy to try things, if I can convince myself they're reasonably safe. That was a few weeks ago, and I'm happy to report that my floor is noticeably cleaner and my teeth cared for =) I could try to claim other less measurable and subjective benefits, but that wouldn't be very honest with myself after only a couple weeks, and I doubt you'd believe me.
travisjungroth 6y ago
If someone is impaired to drive they are by definition not microdosing. The equivalent to alcohol would be like a quarter of a beer.