3 ms·
It's very hard to take toxic amounts of vitamin D: > "Taking 60,000 international units (IU) a day of vitamin D for several months has been shown to cause toxi
by bpodgursky 6y ago
It's very hard to take toxic amounts of vitamin D:
> "Taking 60,000 international units (IU) a day of vitamin D for several months has been shown to cause toxicity. This level is many times higher than the U.S. Recommended Dietary Allowance (RDA) for most adults of 600 IU of vitamin D a day.
(https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/vitamin-d-toxicity/faq-20058108 https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-h...)
Not saying it's impossible, but that's the equivalent of buying the top result on amazon (https://www.amazon.com/Nature-Made-Vitamin-Strength-Softgels/dp/B008GC9T6A https://www.amazon.com/Nature-Made-Vitamin-Strength-Softgels...) and taking 12 polls a day for several months. It's not actually impossible to get to toxic levels... but that's a serious commitment.
- mlyle 6y agoAcute toxicity is not the only risk. E.g. risks of bone fractures increase at a few thousand IU a day.
- dqv 6y agoIs that with or without vitamin K2 co-supplementation?
- Alex3917 6y agoThe toxic dose is 4,000 IU per day though, so you would normally want to be taking well below that except maybe on a short-term basis.
- fencepost 6y agoThat seems low, considering that 5000iu softgels are very readily available (eg the vit D supplements at Costco). Edit: acute toxic dose not established, chronic toxic dose >50k iu/day. https://www.medscape.com/answers/819426-102369/at-what-dose-is-vitamin-d-toxic https://www.medscape.com/answers/819426-102369/at-what-dose-... Edit2: this article lists 4000 IU/day as the generally recognized as safe level https://www.healthline.com/nutrition/vitamin-d-side-effects#1.-Elevated-blood-levels https://www.healthline.com/nutrition/vitamin-d-side-effects#...
- tortasaur 6y agoCostco's vitamin D softgels are 2000 IU, not 5000.
- ghaff 6y ago5000 IU softgels are definitely sold OTC though: https://www.naturewise.com/products/vitamin-d3-5000-iu-360-ct https://www.naturewise.com/products/vitamin-d3-5000-iu-360-c...
- fencepost 6y agoNature's Bounty D3 125mcg (5000IU), Costco item #1106007 So not Kirkland Signature, but sold there.
- calvano915 6y ago4000 IU is the tolerable UL (upper limit).
- shock 6y agoAs far as I'm aware Vit D toxicity has been observed in much higher doses than 4000 IU/day. Do you have a quote for the 4000 IU/day figure? The skin produces up to 10,000 IU/day after exposure to UV light⁰. The same study I'm quoting shows toxicity levels at over 20000 IU/day for adults. One person in the study has taken 156,000–2,604,000 IU/day for 2 years! ⓪ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115827/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115827/
- viraptor 6y agoThe production in the body is self-regulating though, so you can't overdose from sun exposure. Supplements can bring you over the limit, because you absorb what you're given.
- shock 6y agoYou are arguing a point I didn't make. My point was to his statement that 4000 IUs/day were toxic (without stating any basis for that number), while the study I quote claims that the body produces up to 10000 IUs/day – so clearly the toxicity limit is not an unqualified 4000 IUs/day. Perhaps in some people toxicity appears at lower doses while in other people at higher doses.
- viraptor 6y agoI'm not really disputing the 4k not being toxic. Just the way I understand it, even though you can produce up to 10kUI through the skin should have no relation to the toxicity level being below or above 10kUI.