4 ms·
Yeah, I was most concerned about controlling for BMI, since ~all of the prior evidence for sex differences didn't/couldn't do it. They controlled for BMI in co
by timr 6y ago
Yeah, I was most concerned about controlling for BMI, since ~all of the prior evidence for sex differences didn't/couldn't do it.
They controlled for BMI in cohort A, and performed an adjusted analysis in cohort B, so I'm somewhat satisfied on that front.
- microcolonel 6y agoBMI isn't exactly comparable between the sexes, since males and females have different distributions of adipose and visceral fat, and the impacts of these are clearly different.
- timr 6y agoThose kinds of effects would presumably count as "gender-specific differences". Previous investigations never really took body mass into account at all, which was...bad.
- rsynnott 6y agoAnd that could maybe contribute to something. There were other studies, though, which didn't take BMI into account at all, even though high BMI is a known risk factor, and generally more men are obese than women.
- pkaye 6y agoI saw this study from southern California. They provide risk ratios for different factors. Seems just being male have a higher risk ratio than being overweight. https://www.acpjournals.org/doi/10.7326/M20-3742#f1-M203742 https://www.acpjournals.org/doi/10.7326/M20-3742#f1-M203742