5 ms·
There's more than a few clues that at least some depressions, or rather - depression like states - on short timescales are closely related to our brains dynamic
by lostmyoldone 6y ago
There's more than a few clues that at least some depressions, or rather - depression like states - on short timescales are closely related to our brains dynamic "electrochemical" state than of anything else, as disrupting the dynamics in different ways appear to - sometimes - profoundly affect depressed states.
On longer timescales it seems even more complex. Similarly to ECT, some people revert to a depressive state somewhat quickly after being affected by various drugs, while others do not.
I sometimes think that when we start understanding depression, we'll have to reevaluate our perspectives on both ourselves, society, and humanity as such much more than most are comfortable with.
Not in any mysterious sense, but more in the sense that depression on an individual level might very well be a symptom of society level issues, as well as it is an extremely debilitating psychiatric condition.
While there are markers for depression in individuals, I can't escape the feeling that to some extent, it's nothing but a convoluted way to encode tolerance levels to what is in reality a "toxic" surrounding. Exactly what the toxicity could be is not at all clear, but I don't expect it'll have a high compatibility with eg economic interests in any way, shape, or form.
- pas 6y agoThis seems very interesting, could you point at some sources for this? Thanks!
- mrfusion 6y agoI get super depression on the day after I exercise way too much. Especially jogging or sprinting and pushing myself. Too much weight lifting too. I’ve always found it to be the strangest thing and it was quite a shock when I realized the cause. It clears up completely the third day.
- cultofmetatron 6y agoThis happens to me as well! My working theory is the that I deplete all the dopamine during the run. I'll usually feel total contentment for awhile before it settles in. Since I don't have anything to be depressed about in general, its easy to see it for what it is and wait it out with some nutritious food and sleep. Eat fish after exercise. It helps
- mrfusion 6y agoWow. Neat to hear it’s not just me! I wish someone would study it. I couldn’t find anything last time I searched for it. I’ll try fish next time.
- tasty_freeze 6y ago> Since I don't have anything to be depressed about I think this is a case where a word is used in two different ways and it is important to be clear to keep the intended meaning clear. "I'm depressed that she turned me down" is a very different kind of depression than clinical depression. There doesn't have to be any external negative condition to cause someone to have clinical depression. As far as I know, when people talk about using ketamine to help depressed people, they are talking about hard to treat clinical depression, not the short term state of disappointment or sadness that people also call depression.
- hyperpallium 6y agoSounds like depletion of something, perhaps in the energy metabolism pathway, such as thyroxine.
- nanomonkey 6y agoThere are some links between inflammation and depression. Perhaps taking an anti inflammatory the day after working out would be helpful. Or instead of training to failure, do one of the work out protocols that specify maintaining control and staying out of injury and inflammation territory, such as the Quick and the Dead, kettle bell protocol.
- nradov 6y agoRoutine use of anti-inflammatory medication isn't a good idea for most people. Inflammation isn't a bad thing, most of the time. It's actually a critical part of the body's repair mechanisms.