8 ms·

> In other words, when you recover from covid-19, you are immune to it. In other words, covid-19 is just like every other virus, in this respect. "Every other

> In other words, when you recover from covid-19, you are immune to it. In other words, covid-19 is just like every other virus, in this respect. "Every other virus" doesn't behave the same in this regard. The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life. Hopefully it's not an issue here, but it's completely unsurprising that people would want to actually research it instead of just declaring all viruses are the same. The only fools here are the people whose impatience leads them to declare absolutes ahead of times instead of taking preventive measures while the research plays out. https://www.npr.org/sections/goatsandsoda/2020/03/20/819038431/do-you-get-immunity-after-recovering-from-a-case-of-coronavirus https://www.npr.org/sections/goatsandsoda/2020/03/20/8190384... > Researchers do know that reinfection is an issue with the four seasonal coronaviruses that cause about 10 to 30% of common colds.

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f38zf5vdt 7y ago
Yes. It's suspected that immunity is very short lived. > This study provides evidence that re-infections with the same endemic coronavirus are not atypical in a time window shorter than 1 year and that the genetic basis of innate immune response maybe a greater determinant of infection severity than immune memory acquired after a previous infection. http://www.columbia.edu/%7Ejls106/galanti_shaman_ms_supp.pdf http://www.columbia.edu/%7Ejls106/galanti_shaman_ms_supp.pdf Even if you recover, there's not a lot of evidence now as to what the duration of immunity will be. With this spreading through the world at different paces, it means that, as commonly predicted, we will see continuous re-emergence as we do with other cold viruses and influenza.
- CyanLite2 7y ago
  Recovered patients from SARS-1 had long-term antibodies in good concentrations until about 3 years after the infection. We can expect about the same since both coronaviruses are so similar. Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851497/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851497/
- rootusrootus 7y ago
  Maybe we will end up putting this new vaccine research to good use and see if we can knock out some of the other coronaviruses. I'd love a combo vaccine that immunized against a bunch of common cold variants.
timr 7y ago
"it's completely unsurprising that people would want to actually research it instead of just declaring all viruses are the same. The only fools here are the people whose impatience leads them to declare absolutes ahead of times instead of taking preventive measures while the research plays out." This hypothesis ("SARS-Cov19 does not confer immunity") falls roughly under the same category as intelligent design: the claim is so exceptional that it's a priori unlikely to be found true, and laypeople are taking normal scientist hedge-speak and exaggerating the meaning in their heads (e.g. "evolution is just a theory"). There was never really any question to anyone with any serious scientific training that humans would develop some degree of immunity to this virus. That's why people were saying it was more likely to be assay error from the start. The only open question here is how long that immunity might last. Even then, it's fairly clear that short-term (~months to a year) immunity is highly likely. (Note: I have a doctorate in biochemistry with a specialty in molecular biology, and I've studied virology and immunology. I'm not just tossing off uninformed opinions.)
- exolymph 7y ago
  > this falls roughly under the same category as intelligent design debate: the claim is so exceptional that it's a priori unlikely to be found true No. As the person you're responding to pointed out: "The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life."
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  - timr 7y ago
    "No. As the person you're responding to pointed out: "The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life."" Yes. I'm talking about the question of immunity, not whether or not it's possible to get re-infected by new strains of the same virus, or whether or not immunity fades over time. It would be unlikely that this virus didn't confer at least short-term immunity to the host. The viruses that cause colds primarily re-infect because they mutate at a very high rate. We aren't seeing that with this particular virus.
Wowfunhappy 7y ago
> The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life. Yes, but you're almost always immune for at least a year. By then, we should be getting close to a vaccine. And when you do get one of those viruses again, it's significantly less severe the second time.
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f38zf5vdt 7y ago

Yes. It's suspected that immunity is very short lived. > This study provides evidence that re-infections with the same endemic coronavirus are not atypical in a time window shorter than 1 year and that the genetic basis of innate immune response maybe a greater determinant of infection severity than immune memory acquired after a previous infection. http://www.columbia.edu/%7Ejls106/galanti_shaman_ms_supp.pdf http://www.columbia.edu/%7Ejls106/galanti_shaman_ms_supp.pdf Even if you recover, there's not a lot of evidence now as to what the duration of immunity will be. With this spreading through the world at different paces, it means that, as commonly predicted, we will see continuous re-emergence as we do with other cold viruses and influenza.

CyanLite2 7y ago
Recovered patients from SARS-1 had long-term antibodies in good concentrations until about 3 years after the infection. We can expect about the same since both coronaviruses are so similar. Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851497/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851497/
rootusrootus 7y ago
Maybe we will end up putting this new vaccine research to good use and see if we can knock out some of the other coronaviruses. I'd love a combo vaccine that immunized against a bunch of common cold variants.

timr 7y ago

"it's completely unsurprising that people would want to actually research it instead of just declaring all viruses are the same. The only fools here are the people whose impatience leads them to declare absolutes ahead of times instead of taking preventive measures while the research plays out." This hypothesis ("SARS-Cov19 does not confer immunity") falls roughly under the same category as intelligent design: the claim is so exceptional that it's a priori unlikely to be found true, and laypeople are taking normal scientist hedge-speak and exaggerating the meaning in their heads (e.g. "evolution is just a theory"). There was never really any question to anyone with any serious scientific training that humans would develop some degree of immunity to this virus. That's why people were saying it was more likely to be assay error from the start. The only open question here is how long that immunity might last. Even then, it's fairly clear that short-term (~months to a year) immunity is highly likely. (Note: I have a doctorate in biochemistry with a specialty in molecular biology, and I've studied virology and immunology. I'm not just tossing off uninformed opinions.)

exolymph 7y ago
> this falls roughly under the same category as intelligent design debate: the claim is so exceptional that it's a priori unlikely to be found true No. As the person you're responding to pointed out: "The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life."
- deleted 7y ago
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- timr 7y ago
  "No. As the person you're responding to pointed out: "The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life."" Yes. I'm talking about the question of immunity, not whether or not it's possible to get re-infected by new strains of the same virus, or whether or not immunity fades over time. It would be unlikely that this virus didn't confer at least short-term immunity to the host. The viruses that cause colds primarily re-infect because they mutate at a very high rate. We aren't seeing that with this particular virus.

Wowfunhappy 7y ago

> The viruses that cause colds, many of which are also coronaviruses, are pretty adept at hitting people throughout their life. Yes, but you're almost always immune for at least a year. By then, we should be getting close to a vaccine. And when you do get one of those viruses again, it's significantly less severe the second time.

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