4 ms·
Bad News Wrapped in Protein: Inside the Coronavirus Genome
- mancerayder 7y agoThere are many things fascinating here. But two struck me: Viral Proofreader · NSP14 As NSP12 duplicates the coronavirus genome, it sometimes adds a wrong letter to the new copy. NSP14 cuts out these errors, so that the correct letter can be added instead. End of the Line The coronavirus genome ends with a snippet of RNA that stops the cell’s protein-making machinery. It then trails away as a repeating sequence of aaaaaaaaaaaaa So this thing has error detection and handling, and an EOF?