The mechanism of respiratory failure is different in COPD vs ARDS (in the case of COVID), hypercarbic vs hypoxemic. There is minimal human research in the use o

The mechanism of respiratory failure is different in COPD vs ARDS (in the case of COVID), hypercarbic vs hypoxemic. There is minimal human research in the use of NPV/iron lungs with ARDS. As far as I’m aware the technology does not even exist for many of the ventilation modes we use today with NPV which was designed for people with polio and paralyzed breathing muscles rather than “fluid in their lungs” causing the respiratory failure.