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I was watching this clip of Michael Osterholm on Joe Rogen: https://youtu.be/B6IgMdsZHbM https://youtu.be/B6IgMdsZHbM He said the covid-19 would eventually sl
by melling 7y ago
I was watching this clip of Michael Osterholm on Joe Rogen:
https://youtu.be/B6IgMdsZHbM https://youtu.be/B6IgMdsZHbM
He said the covid-19 would eventually slow once enough people get it then we’ll have sufficient immunity that it won’t spread.
Of course, he also said a lot of people are going to get it and we’re at the very beginning of a multi-year problem.
- ajross 7y agoYes, realistically the world will be playing whack-a-mole over the coming months as city after city experiences an outbreak that saturates its health care facilities and has to lock down. It will seem endless. But with each outbreak more people will acquire immunity, and eventually the peaks will be lower than capacity. But it's going to be a rough road to get there, and we'll all suffer on some level. This isn't going to be "over" for quite some time.
- melling 7y agoIt doesn’t affect each age group uniformly. If you’re under 30 without any other health issues, you should be fine? Might not realize you have it? I wonder if it would be easier to create a low dosage vaccine for younger people, thus creating a bit of a firewall so it doesn’t spread as rapidly. I know nothing about medicine so this may be silly.
- rogerkirkness 7y agoGenerally speaking, all vaccines are low dosage. Everyone having the vaccine would be better, starting with those most at risk. If we had a vaccine, we would give it to 80 year olds first, then go down the chain.
- Retric 7y agoYou generally start with healthcare workers, then high risk populations, then the general public.
- deleted 7y ago[deleted]
- paulmd 7y agoDr Anthony Fauci has been estimating it'll take about 12-18 months to get a vaccine through trials. Human testing starts in a month or two. https://www.nytimes.com/2020/03/08/health/fauci-coronavirus.html https://www.nytimes.com/2020/03/08/health/fauci-coronavirus.... We have a ways to go before a vaccine is available. iirc he reiterated this to congress this morning before hearings were terminated to allow Trump to hold a press conference. Witnesses were told to stop their testimony and leave immediately. > “This morning we were informed that President Trump and Vice President Pence have called our witnesses to an emergency meeting at the White House,” Maloney said. “We don't know the details, just that it is extremely urgent.” > At about 11:30 a.m., she ended questioning from lawmakers, saying she received notice from the White House that the witnesses needed to leave “now.” https://thehill.com/homenews/house/487014-trump-officials-cut-testimony-short-at-coronavirus-hearing https://thehill.com/homenews/house/487014-trump-officials-cu...
- mhb 7y agoIt's not silly. Though I'd be interested in the comparison of under-30 without any health issues to over-50 without any health issues.
- maxerickson 7y agoThe current goal is to create any vaccine that is safe and effective. If you have that, you give it to everybody you can. I guess deciding what safe enough is can be a problem (for many people the bar will be "getting the vaccine has better odds for a good outcome than getting the infection", but that is sort of a minimum).
- supercanuck 7y ago>without any other health issue I think people are underestimating what an over-capacity, health care system looks like and the increase in risk of other infections can have.
- bryanrasmussen 7y agoright, as I understand the information from Italy right now emergency services are basically shut down because system overburdened. So as a healthy 30 year old, don't go do any of those healthy sports you like because you might get an injury and that's it then. Also patient 1 in Italy was a healthy marathon runner who at least ended up in intensive care, not sure if dead yet or not.
- giovan-ni 7y agohe is breathing on is own since yesterday, still hospitalized
- bryanrasmussen 7y agothanks for the info!
- lultimouomo 7y agoIn Lombardy, the only region where the situation is critical at the moment, emergency service have NOT shut down. Non urgent procedures are suspended, both to spare doctors and nurses and to avoid creating new emergencies in case those procedures go wrong. ERs are not overwhelmed, ICUs are. You basically get in real trouble if you need a respirator - they're pretty much out of those and they have to assess your chance of survival to decide if they can tube you. Interestingly ERs are seeing much less load because people have stopped going there for stupid reasons, because they are afraid of catching COVID-19. All medical stuff is still busting their ass if course, a lot of them have been lended to ICUs, rooms have been repurposed, etc. This is not to say that the situation isn't bad. It's really bad. And if you think that your country has such a good health care system that it will hold better, you should know that Lombardy hospitals are top notch. Whatever your age, stop traveling. If there's been a single case in your region, stop risky behaviors now: don't go shopping, have it delivered. Work from home. Don't use public transit. Teach your parents how to shop online and force them to stay home. Don't shake hands and wash them often.
- williamDafoe 7y agoNot completely true. It can apparently spread to a lower respiratory problem in ANYONE (where it is VERY deadly, 50% mortality rate) it just tends not to do it very often in persons 10-30 yrs old.
- hybrid_cluster 7y agoSource?
- gnulinux 7y agoI've never seen this 50% figure, looking at people in critical condition data, even that's not 50%, more like 20% mortality. Please provide a source, or delete your comment.
- fock 7y agoyeah, I agree that this is no problem if hospitals stop taking anyone over 40 with respiratory issues and leave them to die at home. Letality might approach 10-20% then (from all we know), but hey, we are young!
- andybak 7y agoI'm 49. I wish you'd said "Over 50".
- JamesBarney 7y agoIm 34 so I'll be fine, and I probably won't lose any friends. But I may lose a parent and I'll definitely have a friend who loses a parent. And that seems pretty awful especially considering how preventable this all was.
- jamesrcole 7y ago> so I’ll be fine I hope so, but - it will kill some number of younger people, even healthy ones. - it’s also worth considering that we don’t (AFAIK) have a clear picture about potential long-term complications (eg lung damage). We should not simply assume there won’t be these. I’m saying this to emphasize the seriousness of the situation.
- gambiting 7y ago>>Im 34 so I'll be fine I'm sorry, but that's a stupid assumption to make. I'm "only" 29 and last year I managed to catch a parvovirus B19 from someone - it's a virus that's relatively common in children, but has very mild symptoms - it's almost unheard of in adults, mostly because you either already have immunity, or there are no symptoms/the symptoms are no worse than a mild cold/flu. Well, except that in about 10% of adults it causes severe response with a high fever that last weeks, with arthretic swelling of joints - and in 10% of those the joint issues don't go away for years. Well, it's been nearly a year now and my knees and other joints are still fucked from the virus, I'm constantly on steroids just to control the inflammation. So no, this has changed my "I'm young so I'll be fine" outlook on this - the chances are not always in your favour.
- krageon 7y agoYou're being overly dramatic. While in general you might be correct, in this specific case you are not and your fear mongering isn't helping anyone.
- brigandish 7y agoSorry to hear that. I wish the insight you have could spread further (what a sorrowful irony) but it seems wisdom is rarely won without painful experience, the blasé attitude of some is not helping right now. I hope you get better soon.
- teambayleaf 7y agoThe mortality rate of COVID-19 is estimated to be around ~0.1% for young people, which is five times higher than seasonal flu. > the risk of death among young adults would be smaller than that of older adults, e.g., at most 0.1%–0.2%. Whether to perceive this estimate as severe or moderate is a matter for discussion, but we consider 0.1%–0.2% among young adults to be unusually high. > https://www.mdpi.com/2077-0383/9/2/580 https://www.mdpi.com/2077-0383/9/2/580 So although it is not as deadly as SARS (which had 20% fatality rate), you definitely don't want to catch it.
- lixtra 7y ago> we consider 0.1-0.2% ... high To put that into perspective that’s the mortality rate of measles [1] and our grandparents were still going to measls parties. [1] https://www.cdc.gov/vaccines/pubs/pinkbook/meas.html https://www.cdc.gov/vaccines/pubs/pinkbook/meas.html
- ajross 7y agoBut measles wasn't a pandemic! Everyone keeps thinking this is about individual risk and trying to downplay things, and it's not like that. Our grandparents went to measles parties because they knew that they'd eventually be exposed and wanted to do it under controlled conditions where they knew treatment was available and had a plan for early detection of symptoms. The situation with COVID-19 is that people who get sick are going to do so in an environment where they and their government are surprised as "how fast it grew" and where all the hospital beds (and oxygen masks, and ventilators, and intubation kits, and doctors, and nurses, and...) are going to be filled by other sick people. And a lot of them are going to die, who didn't need to if we had just taken this seriously and not told people "it's just like measles".
- lixtra 7y agoMy reading of melling was to actually infect young and healthy people under controlled circumstances such that herd immunity builds. To that teambayleaf pointed out that it comes at high individual risk. But in the past this was done for measles at similar risk.
- lllr_finger 7y agoAn otherwise healthy thirtysomething in Minnesota is in critical condition right now - it's not time to panic but you probably want to avoid getting this if you can.
- qznc 7y agoThat would be the good scenario because then we can move the critical ICU equipment from outbreak to outbreak. The bad scenario is if it becomes too much. China sending equipment to Italy now is a good sign.
- saiya-jin 7y ago> But with each outbreak more people will acquire immunity, and eventually the peaks will be lower than capacity. Last time I checked there are at least 3 or 4 different strains circulating now. That's why some folks who got cured got it again. So don't have such naive hopes that all will be rosy on its own soon. If the story will be similar to flu, we're pretty much fucked - every year the strain is so different that prior vaccinations/immunity doesn't work on them. I certainly hope that's not the case, too early to tell.
- op00to 7y agoTwo strains. Stop spreading rumors.
- animal531 7y agoI'm looking at: https://nextstrain.org/ncov https://nextstrain.org/ncov What defines a strain? I know about the L/S sub-types, but there have been a great number of splits.
- saiya-jin 7y agoExactly. Anyway, the topic is that simply getting through the infection doesn't grant immunity so one doesn't have to care about covid-19 anymore. Plus thinking that when we have few (even if 2) variants of the virus within first 3 months there won't be any more mutations is a bit naive IMHO.
- ajross 7y agoRealistically it's more than that, though. Viruses mutate rapidly and this one is into the hundreds of thousands of human transmissions now and still picking up steam. We just don't have the PCR bandwith available to sequence them as fast as they're spreading. Pretty much any direct pronouncement on the "kinds" of SARS-CoV-2 is going to be speculation, so it's all "rumors". But strains don't correlate perfectly to immune respnse, so the upthread point about reinfection risk remains speculation. We just don't know yet. But all endemic viruses eventually reach equilibrium with the population immune response (and vaccination regime), even if it requires regular updates a-la the yearly change in flu shots.
- the6threplicant 7y agoIn other words it's following a logistics curve. This is what every pandemic does: the problem is that we can't know when the inflection point is. Sometimes it's quite early on, and sometimes it isn't. Plan for the latter, hope for the former.
- jmkni 7y agoWhat do you mean by inflection point, and why is it better if it's early?
- ryukafalz 7y ago3Blue1Brown has a recent video on this that explains it really well: https://youtu.be/Kas0tIxDvrg https://youtu.be/Kas0tIxDvrg
- usrusr 7y agoEarly can mean "at a low percentage" (which would be good) and not just "reached fast" (which would be very bad, unless also at low percentage). The percentage is directly depending on R0 (which apparently isn't easy to get below 1 even with China-grade measures).
- tibu 7y agoThe inflection point here means that the speed of the spreading of virus gets slower, so less people get infected then previous day. If this point is earlier in time, this means that the virus won't infect so many people after a time. I think the big question is the cause of the inflection point. Is it because of the nature of the virus or because of the different action like quarantine
- usrusr 7y agoIf official numbers are less than 90% off even Wuhan hasn't reached anything close to saturation yet.
- jeromegv 7y agoThat's because they took measures to stop it, same as South Korea, where the USA has not.
- kerabatsos 7y agoIt will be difficult to convince the 40% of the population that measures need to be taken when that 40% thinks everything of consequence is a hoax, fake news, etc - being incited and reinforced by their Dear Leader. It's the result of a decades long undervaluing, underfunded, ignored education system.
- omarhaneef 7y agoDoes this mean it is better to get it very early before the health system stresses out (might be too late for that and this is a selfish sort of thing anyway), or medium early before you are so old that your immune system is crap, or very late when they have effective vaccines. Anytime but right now, basically.
- tpfour 7y agoIf you are part of a high mortality rate demographic, you are better to get it first in your demographic to have a better access to resources (or very late when the resources are back under control). The issue is not really the virus per se, but its effect on the healthcare systems. That is something health systems work with _every year_ with flu season, nothing new under the sun. What's different is _nobody_ has immunity to this virus, and a lot of people initially dismissed the virus, or are still dismissing the risks.
- eveningcoffee 7y agoI think it is like with everything else - it depends. If you are in the high mortality rate demographic and your recovery is not fast enough then you may still have the risk of being "phased out" when the medical system comes crashing down with the load of new cases happening during your recovery. The best is to not get the infection.