5 ms·
Study finds dopamine, biological clock link to snacking, overeating and obesity
- dooglius 7y agoIn mice
- Someone1234 7y agoJust to clarify the title a little "biological clock" in this circumstance isn't about lifespan, it is about your body's natural desire to eat (specifically when to eat). They found, in mice, that high-calorie diets at meals resulted in eating more often between meals. From the article: > Güler's team found that mice fed a diet comparable to a wild diet in calories and fats maintained normal eating and exercise schedules and proper weight. But mice fed high-calorie diets laden with fats and sugars began "snacking" at all hours and became obese. I'd wonder though if they're re-measuring the gut bacteria phenomenon that has previously been observed. Essentially your gut bacteria can encourage you to eat certain foods, if you eat too much of one kind of food you over-bread that specific bacteria (and suppress others) resulting in a "waterfall" over desire for the food that bacteria need. https://www.nature.com/articles/4441009a https://www.nature.com/articles/4441009a https://www.sciencedirect.com/science/article/abs/pii/S0369811407002210 https://www.sciencedirect.com/science/article/abs/pii/S03698...
- luxuryballs 7y agoFunny, the same thing happens to my cats if I leave dry food out for them versus feeding them wet food at morning and night.
- jacobush 7y agoWhat happens, in which case do they eat more?
- luxuryballs 7y agoThey get fat from eating the always available dry food. Wet food is way better for them, high moisture and protein, dry food is typically the equivalent of the junk food.
- jacobush 7y agoI'm glad I asked. With my dog, it's the opposite. He binges wet food. Dry food I leave a bowl full at all times. He eats when he's hungry, no binging. Thought - cats typically need higher quality food than dogs, dogs are much more opportunistic. (And more similar to us in that respect, I guess.)
- luxuryballs 7y agoThat makes sense to me, my dog will eat until full, sometimes if she manages to find some scraps she won’t finish her dry food (we give her 3/4 cup day and night). Curious about the dog binging on wet food, how much are you making available?
- jacobush 7y agoRarely, it's a novelty and he loves it. But he gets an upset stomach, so I've gone back to (best quality I could find, no grain etc) dry food. I think for him, wet dog food and "found" human food are equally delicious. He likes the dry food too whenever I switch flavor, but tires of it over the weeks the bag lasts.
- ericabiz 7y agoThere's a documentary (free on Amazon Prime) called "Fasting" that touches on this same hypothesis. Basically, our bodies are wired to eat late morning to early evening. Calories consumed outside of those hours are much more likely to turn into fat. Optimum eating window is somewhere around 11AM or noon for most people to 6PM at the latest. When people reduce their eating window, without counting calories or doing anything else, they often lose weight. This is gaining popularity as "intermittent fasting." I definitely recommend the movie if you want to learn more--it kept me engaged the entire time. I've also done 2 cycles of ProLon (mentioned in the movie and has significant scientific backing) to boost my own immune system, so I'm a believer in fasting as a health benefit.
- moretai 7y agoWhat exactly is ProLon? Is it just moving your feeding window to 11am-6pm? I searched on Google but the first few links offer no insight except the impression I might have to pay money to learn more.
- rladd 7y agoIts the commercialization of this: A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan https://www.cell.com/cell-metabolism/fulltext/S1550-4131(15)00224-7 https://www.cell.com/cell-metabolism/fulltext/S1550-4131(15)... You can do it yourself without any kind of kit, if you count calories. I've done it 7 times so far. Due for another one soon.
- masonic 7y agoThis is gaining popularity as "intermittent fasting." No, the proper term for this is "time-restricted feeding".
- Bartweiss 7y agoThanks for pointing out the distinction here. Regardless of how we define each term, there's a notable difference between normal eating within constrained hours and unsustainable/varied patterns between days. The "metabolic switch" rationales for periodic/daily fasting don't apply to time-restricted eating, nor do some of the insulin/glucose theories, but the circadian ones work for both.
- gwn7 7y agoIt is great to see this kind of studies being done, as they are against the best interests of big food companies who usually don't care about the public health. This phenomenon is already known in many circles but is still being rejected regularly by some people as not being backed by sufficient scientific data. Well here is some data. Hope to see more of it.
- jkhdigital 7y agoTo be fair, starvation was a much more pressing problem than obesity for most of human history, so cheap and efficient delivery of calories is a pretty monumental achievement of industrialized agriculture. To paraphrase Harvey Dent, the big food companies have stuck around long enough to see themselves become the villains.
- gwn7 7y ago> To be fair, starvation was a much more pressing problem than obesity for most of human history, so cheap and efficient delivery of calories is a pretty monumental achievement of industrialized agriculture. I have to agree that this really is a monumental achievement. Calorie-dense food is no longer scarce but in abundance. We are not hearing much about starvations at least in the "developed world". But on the flip side many people now have some kind of metabolic disease. Nearly everybody in my family is suffering from at least one metabolic disease mainly caused by a compromised sugar metabolism which in turn is caused by processed foods. And this is really causing a great suffering. So the solution to the original problem begot a new kind of problem. Is the new problem better than the original one? Debatable. Now we can support a much larger population much more easily (which is just what we need). But a population that is a lot less healthy than the previous generations. Quality is in decline. Anyway it's still "progress", and yeah, a monumental one. If only they knew where to stop. They never do...
- ilaksh 7y agoAs someone who has recently starting dealing with a somewhat significant weight problem, I would like to disagree with the premise a little bit. I have put on quite a lot of weight recently as a result of two simple things: one, I am older. This probably is not a big part of it. Two, I just stopped exercising for a few months. Meaning, I have not even been doing my daily walks. I don't often eat snacks or really large meals. Sometimes only one meal in a day. But since I often don't move around _at all_ except for minimal tasks, and have spent a lot of time sitting at the computer, I have been putting on weight rapidly. So yeah, my New Years resolution is to go back to walking every day.