7 ms·

Peter Attia talks about this indirectly, where he’s been to some chemo floors and observed patients taking “healthy” drinks and supplements that are mixed as a

by whb07 7y ago

Peter Attia talks about this indirectly, where he’s been to some chemo floors and observed patients taking “healthy” drinks and supplements that are mixed as a milkshake of sugar and carbs. Problem is a number of the cancer cells can only live on glucose. The other pathways for energy are broken/nonexistent, and so consumption of sugary drinks directly feeds fuel to these type of cells. Strange how the field hasn’t connected the dots yet. 1. Prove the cancer cells of X type can only feed on glucose 2. If so, don’t ingest glucose. Radical science here folks

deleted 7y ago
[deleted]
nradov 7y ago
Your comment isn't relevant to this article. The study was about vitamins and antioxidants, not carbohydrates.
- ComputerGuru 7y ago
  I think he’s referring to the method of ingestion. A lot of supplements come in different forms, including sweetened chewables and drink mixes.
selimthegrim 7y ago
I think Otto Warburg might have beaten you to it
spac 7y ago
Do you work in oncology or medicine?
- spac 7y ago
  This reply was downvoted, and I am a bit surprised: I would expect that making a strong claim of naivete of an entire field of people dedicating their life to a problem (oncology) should be at least put in context of the commentator's expertise and evidence (see the other Metformin related comment). I hope this is seen as a constructive comment: let's not abandon the respect for expertise.
  - aiphex 7y ago
    I can appreciate the inquiry, but I would expect a senior biology undergrad to be able to write a comprehensive paper on a topic like this based solely on the information that's been published.
  - dang 7y ago
    If you post a comment like that just as a one-liner, it's much too easy to interpret it as snark or personal attack. That's destructive of good conversation on the internet. If you provide more information about your intent, as you did in your second comment, that helps to prune the response tree of defensive or aggressive replies, and we all benefit.
rubyfan 7y ago
Do you have evidence beyond indirect second hand anecdotes that might support your hypothesis?
- nabla9 7y ago
  I think op is only partially right. There seems to be indirect connection trough insulin and insulin like growth factors. They can play important role in oncogenesis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/
- aiphex 7y ago
  This is not new information. And it's been shown to be efficacious. The problem is patient adherence. Chemo is something that so long as the patient shows up you can administer it and they can go back home. A glucose free diet could only be adhered to on an in-patient basis. Which most patient / healthcare systems cannot afford. There have also been studies showing efficacy of a compound which down regulates Glut1 in order to cut off glycolysis in cancer cells which rely solely on it for energy production.
  - whatshisface 7y ago
    >A glucose free diet could only be adhered to on an in-patient basis. That's not true, the Keto diet is a big fad and it only works if your diet is basically glucose free.
    - JoeAltmaier 7y ago
      Dieting is notoriously difficult to follow 100%. And in this case that's important. In-patient, the intake is exactly what the dietician (and indirectly the doctor) prescribes. A better outcome could be expected.
    - firethief 7y ago
      I have doubts about a couple of the assumptions implicit in this statement. - The "Keto" diet particularly works. Last time I checked, the research suggested it worked about as well as any other elimination diet, or vanilla CR. - The reason it works. Given that it works about as well as any other elimination diet, it's probably important for practitioners to adhere strictly, rather than continuing to consume the foods that made them fat; but successfully avoiding carbohydrate intake enough to trigger some particular level of ketosis is probably not a part of how it "works".
RandomInteger4 7y ago
This study mentions antioxidants rather than glucose.
chiefalchemist 7y ago
Not questioning you. But do you have a link to the cancer cell and glucose connection?
- grzm 7y ago
  The Warburg hypothesis should be a good jumping off point: https://en.wikipedia.org/wiki/Warburg_hypothesis https://en.wikipedia.org/wiki/Warburg_hypothesis
jakeogh 7y ago
It's being worked on. As with anyting in living systems, it's not simple. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197057/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197057/
JamesBarney 7y ago
The field has 100% connected the dots. And there are a lot of studies on it, but trying to cure cancer through the Warburg effect isn't quite the holy Grail they hoped.

by whb07 7y ago

deleted 7y ago

[deleted]

nradov 7y ago

Your comment isn't relevant to this article. The study was about vitamins and antioxidants, not carbohydrates.

ComputerGuru 7y ago
I think he’s referring to the method of ingestion. A lot of supplements come in different forms, including sweetened chewables and drink mixes.

selimthegrim 7y ago

I think Otto Warburg might have beaten you to it

spac 7y ago

Do you work in oncology or medicine?

spac 7y ago
This reply was downvoted, and I am a bit surprised: I would expect that making a strong claim of naivete of an entire field of people dedicating their life to a problem (oncology) should be at least put in context of the commentator's expertise and evidence (see the other Metformin related comment). I hope this is seen as a constructive comment: let's not abandon the respect for expertise.
- aiphex 7y ago
  I can appreciate the inquiry, but I would expect a senior biology undergrad to be able to write a comprehensive paper on a topic like this based solely on the information that's been published.
- dang 7y ago
  If you post a comment like that just as a one-liner, it's much too easy to interpret it as snark or personal attack. That's destructive of good conversation on the internet. If you provide more information about your intent, as you did in your second comment, that helps to prune the response tree of defensive or aggressive replies, and we all benefit.

rubyfan 7y ago

Do you have evidence beyond indirect second hand anecdotes that might support your hypothesis?

nabla9 7y ago
I think op is only partially right. There seems to be indirect connection trough insulin and insulin like growth factors. They can play important role in oncogenesis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614012/
aiphex 7y ago
This is not new information. And it's been shown to be efficacious. The problem is patient adherence. Chemo is something that so long as the patient shows up you can administer it and they can go back home. A glucose free diet could only be adhered to on an in-patient basis. Which most patient / healthcare systems cannot afford. There have also been studies showing efficacy of a compound which down regulates Glut1 in order to cut off glycolysis in cancer cells which rely solely on it for energy production.
- whatshisface 7y ago
  >A glucose free diet could only be adhered to on an in-patient basis. That's not true, the Keto diet is a big fad and it only works if your diet is basically glucose free.
  - JoeAltmaier 7y ago
    Dieting is notoriously difficult to follow 100%. And in this case that's important. In-patient, the intake is exactly what the dietician (and indirectly the doctor) prescribes. A better outcome could be expected.
  - firethief 7y ago
    I have doubts about a couple of the assumptions implicit in this statement. - The "Keto" diet particularly works. Last time I checked, the research suggested it worked about as well as any other elimination diet, or vanilla CR. - The reason it works. Given that it works about as well as any other elimination diet, it's probably important for practitioners to adhere strictly, rather than continuing to consume the foods that made them fat; but successfully avoiding carbohydrate intake enough to trigger some particular level of ketosis is probably not a part of how it "works".

RandomInteger4 7y ago

This study mentions antioxidants rather than glucose.

chiefalchemist 7y ago

Not questioning you. But do you have a link to the cancer cell and glucose connection?

grzm 7y ago
The Warburg hypothesis should be a good jumping off point: https://en.wikipedia.org/wiki/Warburg_hypothesis https://en.wikipedia.org/wiki/Warburg_hypothesis

jakeogh 7y ago

It's being worked on. As with anyting in living systems, it's not simple. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197057/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197057/

JamesBarney 7y ago

The field has 100% connected the dots. And there are a lot of studies on it, but trying to cure cancer through the Warburg effect isn't quite the holy Grail they hoped.