4 ms·
That result is pretty weak statistically and the phenotype is vague. (Yes it passes GWAS threshold but a lot of associations do that are later found to be false
by searine 7y ago
That result is pretty weak statistically and the phenotype is vague. (Yes it passes GWAS threshold but a lot of associations do that are later found to be false positives).
Symmetry would be an easy "attractive" metric, but these are all complex traits that we aren't really close to narrowing down the mechanism for.
- gwern 7y ago> That result is pretty weak statistically and the phenotype is vague. As one would be expected from GWASes with current sizes and noisy measurements. Yet, that's very different from 'never'. > Yes it passes GWAS threshold but a lot of associations do that are later found to be false positives That's not true. Genome-wide statistically-significant hits have excellent replication rates, when calculated properly.