4 ms·
IANAdrugologist but that rule is about bioactivity rather then psychoactivity. Open to correction though.
by tempguy9999 7y ago
IANAdrugologist but that rule is about bioactivity rather then psychoactivity. Open to correction though.
- dekhn 7y agoyou're correct. it doesn't help a lot with predicting psychedelic activity other than to act as a negative filter for unlikely compounds.
- shawnz 7y agoYes, it's just one piece of the puzzle. The op might also be interested in David E Nichols' research into structure-activity relationships of psychedelics. See: https://web.archive.org/web/20080704190159/http://www.heffter.org/review/chapter5.pdf https://web.archive.org/web/20080704190159/http://www.heffte...