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Illumina has been stuck at 1000$ per human genome for a while. New methods are already here, long read sequencing direct from source with minimal preparation [
by alecmg 7y ago
Illumina has been stuck at 1000$ per human genome for a while.
New methods are already here, long read sequencing direct from source with minimal preparation [0]. It doesn't say much about cost, but considering reduced preparation step and smaller equipment it should be a fraction of Illumina.
[0] https://www.nature.com/articles/nbt.4125 https://www.nature.com/articles/nbt.4125
- lkirk 7y agoNanopore sequencers may require less prep and may be cheaper, but their sequencing error rate is astronomical, so you'd end up doing a lot more sequencing of the same material before you reached a consensus sequence.
- DoctorOetker 7y agoI believe the nanopore sequencers would fare a lot better if the parasitic capacitance across the membrane could be minimized, by decreasing their surface area, alternatively fluorescent readout of the pore itself
- waiquoo 7y agohttps://iopscience.iop.org/article/10.1088/0957-4484/27/7/075503 https://iopscience.iop.org/article/10.1088/0957-4484/27/7/07...