I haven't researched Guix specifically, but if you want a package manager for macOS with these features, Nix definitely supports macOS (Nix is the inspiration f

I haven't researched Guix specifically, but if you want a package manager for macOS with these features, Nix definitely supports macOS (Nix is the inspiration for Guix). Even if Guix is supported on macOS, I'm not sure offhand if there's any compelling reason to use Guix over Nix. As near as I can tell, the only reason Guix even exists is because the authors don't like that Nix has a custom language and prefer Guile Scheme instead. Nix: https://nixos.org/nix/ https://nixos.org/nix/