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I am pretty sure that low dose aspirin has some benefits for some people/conditions. At least I remember reading studies that suggest as much. So naturally I w
by whycombagator 7y ago
I am pretty sure that low dose aspirin has some benefits for some people/conditions. At least I remember reading studies that suggest as much.
So naturally I was curious about it being “nonsense” for heart disease.
A quick skim of the article + a quick search shows it’s not as clear cut and conclusive as you suggest.
Interestingly, neither is the increased risk of cancer discussed in the article. Aspirin has been shown to have the opposite effect too.
I found it hard to glean what dosages where used in the studies mentioned in the article but the couple I saw were 100mgs per day. I didn’t see mention of if they were enteric coated or taken with meals.
In the US baby aspirin is 81mg and in the UK there are 75mg available. Both are enteric coated. In Australia it seems 100mg might be considered low dose and widely available.
It would be interesting to see more studies on this topic using lower dose, coated, aspirin taken with a meal. The US/UK low dose aspirin are 19-25% lower than at least a couple of dosages the studies mentioned. Those lower dosages may help mitigate bleeding risk.
Seeing as some of aspirins effects are longer lasting, perhaps alternative dosing schedules could also be looked at (every other day etc.) - this may further help mitigate the bleeding risk whilst still providing benefit.
- Scoundreller 7y agoThe doses were different for legal reasons. Aspirin for children is unnecessarily risky in most cases but different countries set different cutoffs for restricted doses vs. unrestricted adult doses. But ya, dosing is underrated. Something that's bad at X dose may be beneficial at 1/Yth the dose.
- deleted 7y ago[deleted]