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CRISPR's not that hard, this guy did it in his garage. Delivering it to cells is a bit harder, but not that hard unless you're talking brain cells, then the blo
by codeulike 8y ago
CRISPR's not that hard, this guy did it in his garage. Delivering it to cells is a bit harder, but not that hard unless you're talking brain cells, then the blood-brain barrier causes trouble.
https://www.theguardian.com/science/2017/dec/24/josiah-zayner-diy-gene-editing-therapy-crispr-interview https://www.theguardian.com/science/2017/dec/24/josiah-zayne...
- folli 8y agoCRISPR is unrelated to Zolgensma, which uses an Adeno-associated virus to deliver a functioning version of the SMN1 gene.
- codeulike 8y agoI know. I was giving an example of modern biotech
- dekhn 8y agoanybody with a decent level of biochemical knowledge can do these things in a garage (I built a biolab in my garage and work at a lab that does CRISPR). However, the person you cited is clueless and is just kind of injecting things into his body without any really thought to efficacy or safety. There is a big difference between injecting reagents into a single human, and doing actual medicine.
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- Palptine 8y agoTell that to the guy that tried to create HIV resistance babies in China. He had a decent lab yet both babies he created didn't have ccr5 hit: the crispr missed target.
- refurb 8y agoDelivering it to cells is a bit harder That's a bit of an understatement. The difference between doing CRISPR on a cell and a petri dish and doing it in a human is huge. That's why no one has done it yet.