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I know a lot of people who take melatonin to fall asleep. Trying to understand if that's good or bad here?
by braindumps 8y ago
I know a lot of people who take melatonin to fall asleep. Trying to understand if that's good or bad here?
- corysama 8y agoDon’t see anything bad mentioned here. TLDR: Animals with damaged pineal glands have trouble growing hair. Melatonin supplement helps reverse this. Topical melatonin reduces UV damage to the skin and can promote hair growth.
- deleted 8y ago[deleted]
- magrimu 8y ago>Melatonin administration has been found to increase hair growth in a variety of mammals >In a randomized double-blind study of 40 women with hair loss, melatonin solution applied to the scalp increased hair growth significantly relative to placebo Seems like a positive. The article is suggesting that by helping regulate the circadian rhythm, the use of melatonin can potentially: extend lifespan, prolong fertility, reduce cancer incidence, reduce obesity and insulin resistance, improve neurological recovery from brain injury, improve skin resistance to damage (such as from UV rays) and increase hair growth. Unfortunately, this is unlikely to affect male pattern hair loss.
- orliesaurus 8y ago> Unfortunately, this is unlikely to affect male pattern hair loss. Source?
- deleted 8y ago[deleted]
- cooooooffffeeee 8y agoIt's suspected that male pattern hair loss is a combination of genetics and testosterone. Melatonin will not impact your DNA or testosterone levels.
- radus 8y agoAccording to the article, you may be getting more hair and be less susceptible to sun damaged skin. What isn't clear is whether or not taking melatonin orally at typical dosage (300 mcg to 5 mg) will have those effects in humans. It seems that most of those human studies used topical application, and several of the animal studies used melatonin implants. Also, here is a quote from one of the references (Kleszczynski and Fischer, 2012): > Regarding clinical application, exogenous melatonin should rather be used topically than orally, since orally administered melatonin appears in rather low levels in the blood due to prominent first-pass degradation in the liver, thus limiting skin access. Topical application might be meaningful, since melatonin can penetrate into the stratum corneum and build there a depot due to its distinct lipophilic chemical structure. Therefore, endogenous intracutaneous melatonin production, together with topically applied exogenous melatonin or metabolites can be expected to represent one of the most potent antioxidative defense systems against UV-induced skin aging.
- qwerty456127 8y agoNothing is bad in melatonin except the tolerance development. If I wasn't afraid of developing tolerance to endogenous melatonin I would take huge doses of it every evening.
- taneq 8y agoSo you're saying it's pretty much a free lunch?
- therealx 8y agoTolerance, vivid dreams, and anxiety in some.
- scotty79 8y agoNot sure if it'll do anything for you but it surely is safe. My SO is taking 20mg per day for years (for glioma, not insomnia, it's way too high dose to work for insomnia). She had a break from it for few months during which her tumors started regrowing, might be coincidence.
- inciampati 8y agoIt seems like a free lunch because we are starving ourselves for it. We need a lot more than we produce endogenously under artificial night lighting.
- newsbinator 8y agoI find small doses work better than huge doses anyhow.
- inciampati 8y agoI agree. Also, slow release can be similar to small doses in effect.
- ip26 8y agoI have heard that the main questionmark is that typical doses are far larger than your body would normally produce, so you can't just assume it's "normal" or "natural". But nobody has really identified harm yet.