3 ms·

There's scores of evidence and studies about this. Don't feel like looking all of them up. https://www.webmd.com/mental-health/news/20080227/antidepressants-no

• eesmith 8y ago
  And yet there's https://www.sciencedirect.com/science/article/pii/S0140673617328027 https://www.sciencedirect.com/science/article/pii/S014067361... from 2018 (a decade later) which concludes "All antidepressants were more efficacious than placebo in adults with major depressive disorder. Smaller differences between active drugs were found when placebo-controlled trials were included in the analysis, whereas there was more variability in efficacy and acceptability in head-to-head trials." Along with commentaries like https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/benefits-of-antidepressants-news-or-fake-news/687A4E815C8AB2E1CEE1020BF6E8CEBC/core-reader https://www.cambridge.org/core/journals/the-british-journal-... where the abstract is: > Although antidepressant drugs are commonly effective, several meta-analyses of antidepressant drug trials undertaken decades after their introduction suggested that they were effectively acting as placebos. A recent meta-analysis concluded that they were effective. Both conclusions have been widely taken up by the media. This paper seeks to explain the disconnect.